Sodium in the structure of Factor Xa in Complex With A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor (pdb 2xc0)

The binding sites of Sodium atom in the structure of Factor Xa in Complex With A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor (pdb code 2xc0). This binding sites where shown with 5.0 Angstroms radius around Sodium atom. The 2xc0 structure was solved by D.W.BANNER, J.BENZ, D.SCHLATTER, L.ANSELM, W.HAAP, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 74.5-2.0 Space group P43212 a (A) 105.410 b (A) 105.410 c (A) 50.950 alpha (°) 90.00 beta (°) 90.00 gamma (°) 90.00 Rfactor (%) 18.41 Rfree (%) 24.008 Sodium Binding Sites: Sodium binding site 1 out of 1 in 2xc0 Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Sodium in the PDB 2xc0. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Sodium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Tyr185, A: Asp185A, A: Thr185B, A: Lys186, A: Ala221, A: Arg222, A: Lys223, A: Gly223A, A: Lys224, A: Tyr225, A: Hoh2133, A: Hoh2138, A: Hoh2158, conact list: Atom Atom Distance (A) Na O A:Tyr185 2.27 Na N A:Tyr185 4.84 Na CB A:Tyr185 4.94 Na C A:Tyr185 3.44 Na CA A:Tyr185 4.59 Na O A:Asp185A 2.64 Na N A:Asp185A 4.12 Na C A:Asp185A 3.33 Na CA A:Asp185A 3.91 Na N A:Thr185B 4.18 Na C A:Thr185B 4.92 Na CA A:Thr185B 4.58 Na O A:Lys186 4.61 Na O A:Ala221 4.22 Na C A:Ala221 4.05 Na CA A:Ala221 4.56 Na O A:Arg222 2.27 Na N A:Arg222 4.05 Na C A:Arg222 3.37 Na CA A:Arg222 4.31 Na N A:Lys223 4.19 Na C A:Lys223 4.44 Na CA A:Lys223 4.27 Na N A:Gly223A 4.18 Na C A:Gly223A 4.80 Na CA A:Gly223A 4.98 Na O A:Lys224 2.33 Na N A:Lys224 3.74 Na CB A:Lys224 4.69 Na C A:Lys224 3.48 Na CA A:Lys224 4.14 Na N A:Tyr225 4.56 Na CA A:Tyr225 4.82 Na O A:Hoh2133 4.14 Na O A:Hoh2138 2.41 Na O A:Hoh2158 2.62 interactive model: