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Atomistry » Sodium » PDB 2x5x-2xjq » 2xby | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 2x5x-2xjq » 2xby » |
Sodium in PDB 2xby: Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid InhibitorEnzymatic activity of Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor
All present enzymatic activity of Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor:
3.4.21.6; Protein crystallography data
The structure of Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor, PDB code: 2xby
was solved by
D.W.Banner,
J.Benz,
D.Schlatter,
S.Thomi,
W.Haap,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2xby:
The structure of Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor
(pdb code 2xby). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor, PDB code: 2xby: Sodium binding site 1 out of 1 in 2xbyGo back to![]() ![]()
Sodium binding site 1 out
of 1 in the Factor Xa in Complex with A Pyrrolidine-3,4-Dicarboxylic Acid Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
L.Anselm,
D.W.Banner,
J.Benz,
K.Groebke Zbinden,
J.Himber,
H.Hilpert,
W.Huber,
B.Kuhn,
J.L.Mary,
M.B.Otteneder,
N.Panday,
F.Ricklin,
M.Stahl,
S.Thomi,
W.Haap.
Discovery of A Factor Xa Inhibitor (3R,4R)-1-(2,2-Difluoro-Ethyl)-Pyrrolidine-3,4-Dicarboxylic Acid 3-[(5-Chloro-Pyridin-2-Yl)-Amide] 4-{[2-Fluoro-4-(2-Oxo-2H-Pyridin-1-Yl)-Phenyl]-Amide} As A Clinical Candidate. Bioorg.Med.Chem. V. 20 5313 2010.
Page generated: Mon Oct 7 05:08:48 2024
ISSN: ISSN 0968-0896 PubMed: 20650636 DOI: 10.1016/J.BMCL.2010.06.126 |
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