Sodium in PDB 2wy0: Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122

The structure of Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122, PDB code: 2wy0 was solved by A.Zhou, Z.Wei, R.W.Carrell, R.J.Read, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	76.92 / 2.38
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	64.650, 64.650, 461.820, 90.00, 90.00, 120.00
R / Rfree (%)	20.6 / 25.3

The binding sites of Sodium atom in the Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122 (pdb code 2wy0). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 4 binding sites of Sodium where determined in the Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122, PDB code: 2wy0:
Jump to Sodium binding site number: 1; 2; 3; 4;

Sodium binding site 1 out of 4 in the Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122 within 5.0Å range: probe atom residue distance (Å) B Occ C:Na1451 b:53.0 occ:1.00 OE2 C:GLU65 3.0 80.2 1.0 NH2 C:ARG69 3.3 65.5 1.0 CE1 C:HIS13 3.5 65.4 1.0 O C:HIS9 3.7 51.7 1.0 ND1 C:HIS9 3.8 57.0 1.0 NE C:ARG69 3.8 62.4 1.0 CZ C:ARG69 4.0 63.9 1.0 CD C:GLU65 4.0 81.5 1.0 CA C:HIS9 4.1 52.1 1.0 CB C:HIS9 4.1 52.3 1.0 ND1 C:HIS13 4.2 66.9 1.0 C C:HIS9 4.3 51.3 1.0 CG C:HIS9 4.4 54.9 1.0 OE1 C:GLU65 4.6 81.8 1.0 NE2 C:HIS13 4.6 66.1 1.0 NZ C:LYS145 4.7 58.6 1.0 CE1 C:HIS9 4.9 57.3 1.0

Sodium binding site 2 out of 4 in the Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122 within 5.0Å range: probe atom residue distance (Å) B Occ C:Na1453 b:58.3 occ:1.00 OE1 C:GLU31 2.4 48.7 0.1 CD C:GLU31 3.3 49.3 1.0 OE2 C:GLU31 3.9 45.5 1.0 O C:HOH2003 3.9 29.0 1.0 ND1 C:HIS187 4.1 44.8 1.0 CG C:GLU31 4.2 50.1 1.0 N C:SER32 4.2 45.5 1.0 CB C:SER32 4.5 43.6 1.0 CB C:HIS187 4.6 41.4 1.0 CB C:SER188 4.7 42.4 1.0 OG C:SER32 4.7 47.5 1.0 N C:SER188 4.7 40.9 1.0 CA C:GLU31 4.7 49.5 1.0 CG C:HIS187 4.8 43.7 1.0 CA C:SER32 5.0 43.8 1.0

Sodium binding site 3 out of 4 in the Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122 within 5.0Å range: probe atom residue distance (Å) B Occ C:Na1456 b:64.2 occ:1.00 OH C:TYR12 2.6 55.6 1.0 N C:GLY143 3.3 46.0 1.0 CZ C:TYR12 3.7 55.5 1.0 CE2 C:TYR113 3.7 37.3 1.0 CD2 C:LEU114 3.8 38.8 1.0 O C:LEU141 3.8 46.2 1.0 CE2 C:TYR12 4.0 54.7 1.0 CA C:GLY143 4.0 45.0 1.0 CA C:ASP142 4.3 48.4 1.0 C C:ASP142 4.3 46.7 1.0 CD2 C:TYR113 4.4 35.9 1.0 CZ C:TYR113 4.4 39.7 1.0 OH C:TYR113 4.5 43.0 1.0 CG C:LEU114 4.6 37.5 1.0 C C:LEU141 4.7 46.8 1.0 OD2 C:ASP142 4.9 52.9 1.0 CE1 C:TYR12 4.9 56.0 1.0 CA C:LEU114 4.9 36.2 1.0

Sodium binding site 4 out of 4 in the Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 4 of Crystal Structure of Mouse Angiotensinogen in the Oxidised Form with Space Group P6122 within 5.0Å range: probe atom residue distance (Å) B Occ C:Na1457 b:72.4 occ:1.00 O C:HOH2002 2.0 30.2 1.0 CG C:LYS68 4.5 67.8 1.0 CE C:LYS68 4.8 72.8 1.0 CD C:LYS68 4.8 71.5 1.0

A.Zhou, R.W.Carrell, M.P.Murphy, Z.Wei, Y.Yan, P.L.Stanley, P.E.Stein, F.B.Pipkin, R.J.Read. A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature V. 468 108 2010.
ISSN: ISSN 0028-0836
PubMed: 20927107
DOI: 10.1038/NATURE09505