Sodium in PDB 2wge: Crystal Structure of Kasa of Mycobacterium Tuberculosis with Bound Tlm

All present enzymatic activity of Crystal Structure of Kasa of Mycobacterium Tuberculosis with Bound Tlm:
2.3.1.41;

The structure of Crystal Structure of Kasa of Mycobacterium Tuberculosis with Bound Tlm, PDB code: 2wge was solved by S.R.Luckner, C.Kisker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.81 / 1.80
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	77.542, 77.542, 148.458, 90.00, 90.00, 120.00
R / Rfree (%)	16.737 / 20.129

The binding sites of Sodium atom in the Crystal Structure of Kasa of Mycobacterium Tuberculosis with Bound Tlm (pdb code 2wge). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Kasa of Mycobacterium Tuberculosis with Bound Tlm, PDB code: 2wge:

Sodium binding site 1 out of 1 in the Crystal Structure of Kasa of Mycobacterium Tuberculosis with Bound Tlm


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Kasa of Mycobacterium Tuberculosis with Bound Tlm within 5.0Å range: probe atom residue distance (Å) B Occ A:Na1426 b:14.0 occ:1.00 OE1 A:GLU354 2.3 13.2 1.0 OD1 A:ASN399 2.3 10.7 1.0 OD1 A:ASN309 2.4 12.6 1.0 O A:ALA310 2.6 14.2 1.0 O A:ASN309 2.7 12.7 1.0 O A:ASN400 2.7 12.3 1.0 C A:ALA310 3.2 13.1 1.0 C A:ASN309 3.2 13.6 1.0 CD A:GLU354 3.3 12.3 1.0 CG A:ASN309 3.4 13.8 1.0 CG A:ASN399 3.5 12.6 1.0 CB A:GLU354 3.6 11.0 1.0 N A:HIS311 3.7 12.6 1.0 N A:ALA310 3.8 13.0 1.0 C A:ASN400 3.8 12.7 1.0 N A:ASN400 3.8 13.3 1.0 CB A:ASN309 3.9 13.3 1.0 CG A:GLU354 4.0 12.5 1.0 CA A:ALA310 4.0 13.1 1.0 CA A:HIS311 4.0 12.2 1.0 CA A:ASN309 4.2 13.3 1.0 OE2 A:GLU354 4.2 12.7 1.0 ND2 A:ASN399 4.2 14.0 1.0 O A:HOH2263 4.3 16.1 1.0 CA A:ASN400 4.4 12.6 1.0 C A:ASN399 4.5 12.4 1.0 CA A:ASN399 4.5 12.4 1.0 ND2 A:ASN309 4.6 12.3 1.0 CB A:ASN399 4.6 12.2 1.0 CB A:ASN400 4.8 12.7 1.0 NZ A:LYS340 5.0 12.9 1.0 C A:HIS311 5.0 12.1 1.0 N A:SER401 5.0 13.7 1.0

S.R.Luckner, C.A.Machutta, P.J.Tonge, C.Kisker. Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action Within Cell Wall Biosynthesis and Its Inhibition By Thiolactomycin Structure V. 17 1004 2009.
ISSN: ISSN 0969-2126
PubMed: 19604480
DOI: 10.1016/J.STR.2009.04.012