Sodium in PDB 2q93: E. Coli Methionine Aminopeptidase Mn-Form with Inhibitor B21

All present enzymatic activity of E. Coli Methionine Aminopeptidase Mn-Form with Inhibitor B21:
3.4.11.18;

The structure of E. Coli Methionine Aminopeptidase Mn-Form with Inhibitor B21, PDB code: 2q93 was solved by Q.-Z.Ye, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.94 / 1.60
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	39.107, 62.340, 52.441, 90.00, 108.80, 90.00
R / Rfree (%)	22.6 / 25.1

The structure of E. Coli Methionine Aminopeptidase Mn-Form with Inhibitor B21 also contains other interesting chemical elements:

Manganese

(Mn)

2 atoms

The binding sites of Sodium atom in the E. Coli Methionine Aminopeptidase Mn-Form with Inhibitor B21 (pdb code 2q93). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the E. Coli Methionine Aminopeptidase Mn-Form with Inhibitor B21, PDB code: 2q93:

Sodium binding site 1 out of 1 in the E. Coli Methionine Aminopeptidase Mn-Form with Inhibitor B21


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of E. Coli Methionine Aminopeptidase Mn-Form with Inhibitor B21 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na500 b:6.3 occ:1.00 O A:ASN74 2.4 10.1 1.0 O A:VAL76 2.4 7.7 1.0 O A:SER231 2.4 8.5 1.0 O A:HOH517 2.4 7.5 1.0 C A:ASN74 3.2 9.7 1.0 C A:SER231 3.4 8.0 1.0 C A:VAL76 3.5 8.5 1.0 N A:ASN74 3.6 9.2 1.0 O A:HOH501 3.7 9.0 1.0 CA A:ASN74 3.7 10.2 1.0 N A:VAL76 3.9 7.4 1.0 N A:SER231 3.9 7.3 1.0 C A:ILE73 3.9 10.1 1.0 CB A:SER231 3.9 8.0 1.0 CA A:SER231 3.9 8.4 1.0 O A:ILE73 4.1 10.4 1.0 CA A:VAL76 4.2 8.1 1.0 N A:GLU75 4.3 9.2 1.0 O A:SER72 4.3 6.6 1.0 C A:GLU75 4.3 8.0 1.0 N A:VAL77 4.4 8.6 1.0 N A:ALA232 4.5 6.6 1.0 C A:SER72 4.5 7.6 1.0 O A:HOH504 4.5 6.8 1.0 CD1 A:ILE93 4.6 6.4 1.0 CA A:ILE73 4.6 8.6 1.0 CA A:VAL77 4.6 9.1 1.0 CA A:GLU75 4.6 9.2 1.0 N A:ILE73 4.6 7.6 1.0 CG1 A:ILE93 4.7 9.2 1.0 OG A:SER231 4.7 8.1 1.0 CB A:VAL76 4.7 8.1 1.0 CB A:SER72 4.7 8.4 1.0 CE A:MET112 4.9 6.2 1.0 CA A:ALA232 4.9 6.8 1.0 O A:GLU75 4.9 9.3 1.0 O A:ILE93 5.0 9.9 1.0

Z.Q.Ma, S.X.Xie, Q.Q.Huang, F.J.Nan, T.D.Hurley, Q.Z.Ye. Structural Analysis of Inhibition of E. Coli Methionine Aminopeptidase: Implication of Loop Flexibility in Selective Inhibition of Bacterial Enzymes. Bmc Struct.Biol. V. 7 84 2007.
ISSN: ESSN 1472-6807
PubMed: 18093325
DOI: 10.1186/1472-6807-7-84