Sodium in PDB 2q68: Crystal Structure of Nak Channel D66A, S70E Double Mutants

The structure of Crystal Structure of Nak Channel D66A, S70E Double Mutants, PDB code: 2q68 was solved by A.Alam, N.Shi, Y.Jiang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.50
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	82.310, 85.244, 130.212, 90.00, 90.00, 90.00
R / Rfree (%)	24.1 / 26.2

The structure of Crystal Structure of Nak Channel D66A, S70E Double Mutants also contains other interesting chemical elements:

Calcium

(Ca)

2 atoms

The binding sites of Sodium atom in the Crystal Structure of Nak Channel D66A, S70E Double Mutants (pdb code 2q68). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Crystal Structure of Nak Channel D66A, S70E Double Mutants, PDB code: 2q68:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the Crystal Structure of Nak Channel D66A, S70E Double Mutants


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Nak Channel D66A, S70E Double Mutants within 5.0Å range: probe atom residue distance (Å) B Occ A:Na116 b:49.4 occ:0.50 OG1 A:THR63 2.8 41.2 1.0 OG1 B:THR63 2.9 43.4 1.0 O B:THR63 3.0 46.6 1.0 O A:THR63 3.1 47.1 1.0 CA A:CA115 3.4 34.3 0.5 NA A:NA117 3.5 73.5 0.5 CB A:THR63 3.6 44.6 1.0 CB B:THR63 3.7 42.2 1.0 C A:THR63 3.9 38.0 1.0 C B:THR63 3.9 35.3 1.0 CA A:THR63 4.4 38.4 1.0 CA B:THR63 4.5 38.0 1.0 N A:VAL64 4.8 45.7 1.0 CG2 A:THR63 4.8 42.7 1.0 N B:VAL64 4.9 45.6 1.0 CG2 B:THR63 4.9 38.8 1.0

Sodium binding site 2 out of 3 in the Crystal Structure of Nak Channel D66A, S70E Double Mutants


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of Nak Channel D66A, S70E Double Mutants within 5.0Å range: probe atom residue distance (Å) B Occ A:Na117 b:73.5 occ:0.50 O B:HOH117 3.4 83.0 1.0 O B:HOH118 3.4 83.1 1.0 NA A:NA116 3.5 49.4 0.5 OG1 A:THR63 3.9 41.2 1.0 OG1 B:THR63 4.0 43.4 1.0

Sodium binding site 3 out of 3 in the Crystal Structure of Nak Channel D66A, S70E Double Mutants


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Crystal Structure of Nak Channel D66A, S70E Double Mutants within 5.0Å range: probe atom residue distance (Å) B Occ A:Na119 b:79.4 occ:0.50 O A:ALA66 3.3 59.2 1.0 O B:ALA66 3.5 58.4 1.0 C A:ALA66 4.1 62.6 1.0 C B:ALA66 4.3 55.4 1.0 CA A:GLY67 4.4 66.8 1.0 CA B:GLY67 4.5 68.5 1.0 C A:GLY65 4.6 55.1 1.0 C B:GLY65 4.6 45.8 1.0 N A:GLY67 4.6 56.8 1.0 O A:GLY65 4.6 57.8 1.0 O B:GLY65 4.7 54.9 1.0 N B:GLY67 4.8 58.4 1.0 CA B:GLY65 4.8 42.7 1.0 N B:ALA66 4.8 46.8 1.0 N A:ALA66 4.8 62.7 1.0 CA A:GLY65 4.9 46.1 1.0 O A:VAL64 5.0 53.4 1.0 O B:VAL64 5.0 52.9 1.0

A.Alam, N.Shi, Y.Jiang. Structural Insight Into CA2+ Specificity in Tetrameric Cation Channels. Proc.Natl.Acad.Sci.Usa V. 104 15334 2007.
ISSN: ISSN 0027-8424
PubMed: 17878296
DOI: 10.1073/PNAS.0707324104