Sodium in PDB 2pqk: X-Ray Crystal Structure of Human Mcl-1 in Complex with Bim BH3

The structure of X-Ray Crystal Structure of Human Mcl-1 in Complex with Bim BH3, PDB code: 2pqk was solved by E.Bare, R.A.Grant, A.E.Keating, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.60 / 2.00
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	53.087, 71.846, 118.145, 90.00, 90.00, 90.00
R / Rfree (%)	19.4 / 22.9

The structure of X-Ray Crystal Structure of Human Mcl-1 in Complex with Bim BH3 also contains other interesting chemical elements:

Zinc

(Zn)

3 atoms

The binding sites of Sodium atom in the X-Ray Crystal Structure of Human Mcl-1 in Complex with Bim BH3 (pdb code 2pqk). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the X-Ray Crystal Structure of Human Mcl-1 in Complex with Bim BH3, PDB code: 2pqk:

Sodium binding site 1 out of 1 in the X-Ray Crystal Structure of Human Mcl-1 in Complex with Bim BH3


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of X-Ray Crystal Structure of Human Mcl-1 in Complex with Bim BH3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na404 b:36.6 occ:1.00 OD1 A:ASP241 2.3 40.8 1.0 OD2 A:ASP241 2.4 39.7 1.0 CG A:ASP241 2.6 40.4 1.0 OE2 A:GLU240 2.8 48.5 1.0 CD A:GLU240 3.7 46.5 1.0 CG A:GLU240 4.1 43.3 1.0 CB A:ASP241 4.2 40.5 1.0 OE1 A:GLU240 4.6 47.3 1.0 CG A:PRO289 4.9 38.2 1.0 CA A:ASP241 4.9 40.6 1.0 N A:ASP241 4.9 40.4 1.0

E.Fire, S.V.Gulla, R.A.Grant, A.E.Keating. Mcl-1-Bim Complexes Accommodate Surprising Point Mutations Via Minor Structural Changes. Protein Sci. V. 19 507 2010.
ISSN: ISSN 0961-8368
PubMed: 20066663
DOI: 10.1002/PRO.329