|
Atomistry » Sodium » PDB 2p0o-2plo » 2p8s | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 2p0o-2plo » 2p8s » |
Sodium in PDB 2p8s: Human Dipeptidyl Peptidase IV/CD26 in Complex with A Cyclohexalamine InhibitorEnzymatic activity of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Cyclohexalamine Inhibitor
All present enzymatic activity of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Cyclohexalamine Inhibitor:
3.4.14.5; Protein crystallography data
The structure of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Cyclohexalamine Inhibitor, PDB code: 2p8s
was solved by
G.Scapin,
T.Biftu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2p8s:
The structure of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Cyclohexalamine Inhibitor also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Cyclohexalamine Inhibitor
(pdb code 2p8s). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Cyclohexalamine Inhibitor, PDB code: 2p8s: Sodium binding site 1 out of 1 in 2p8sGo back to Sodium Binding Sites List in 2p8s
Sodium binding site 1 out
of 1 in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Cyclohexalamine Inhibitor
Mono view Stereo pair view
Reference:
T.Biftu,
G.Scapin,
S.Singh,
D.Feng,
J.W.Becker,
G.Eiermann,
H.He,
K.Lyons,
S.Patel,
A.Petrov,
R.Sinha-Roy,
B.Zhang,
J.Wu,
X.Zhang,
G.A.Doss,
N.A.Thornberry,
A.E.Weber.
Rational Design of A Novel, Potent, and Orally Bioavailable Cyclohexylamine Dpp-4 Inhibitor By Application of Molecular Modeling and X-Ray Crystallography of Sitagliptin Bioorg.Med.Chem.Lett. V. 17 3384 2007.
Page generated: Tue Dec 15 05:53:48 2020
ISSN: ISSN 0960-894X PubMed: 17433672 DOI: 10.1016/J.BMCL.2007.03.095 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |