Sodium in PDB 2nxb: Crystal Structure of Human Bromodomain Containing Protein 3 (BRD3)

The structure of Crystal Structure of Human Bromodomain Containing Protein 3 (BRD3), PDB code: 2nxb was solved by P.Filippakopoulos, A.Bullock, C.Cooper, K.Keates, G.Berridge, A.Pike, G.Bunkoczi, A.Edwards, C.Arrowsmith, M.Sundstrom, F.Von Delft, S.Knapp, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.94 / 1.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	51.504, 61.840, 84.523, 90.00, 90.00, 90.00
R / Rfree (%)	16.8 / 18.5

The binding sites of Sodium atom in the Crystal Structure of Human Bromodomain Containing Protein 3 (BRD3) (pdb code 2nxb). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Human Bromodomain Containing Protein 3 (BRD3), PDB code: 2nxb:

Sodium binding site 1 out of 1 in the Crystal Structure of Human Bromodomain Containing Protein 3 (BRD3)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Human Bromodomain Containing Protein 3 (BRD3) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na301 b:18.2 occ:1.00 OG1 A:THR36 2.9 20.2 1.0 OE1 A:GLN38 2.9 19.9 1.0 N A:ALA98 2.9 18.3 1.0 OG A:SER97 3.2 20.5 0.5 CB A:ALA98 3.5 18.7 1.0 CB A:THR36 3.6 20.1 1.0 CB A:GLN38 3.7 20.5 1.0 CG2 A:THR36 3.7 19.0 1.0 CA A:SER97 3.8 19.5 1.0 C A:SER97 3.8 18.8 1.0 CA A:ALA98 3.8 18.6 1.0 CD A:GLN38 3.9 20.2 1.0 OE2 A:GLU143 3.9 24.3 1.0 CB A:SER97 4.1 20.3 1.0 O A:HOH391 4.2 22.1 1.0 O A:HOH318 4.2 15.5 1.0 CG A:GLN38 4.3 20.2 1.0 N A:LEU39 4.5 20.1 1.0 CG A:LEU39 4.5 20.2 1.0 CD A:GLU143 4.6 24.0 1.0 CA A:GLN38 4.7 20.4 1.0 CD1 A:LEU39 4.8 21.6 1.0 CG A:GLU143 4.8 22.6 1.0 N A:GLN38 4.8 21.1 1.0 C A:GLN38 4.9 20.8 1.0 O A:SER97 5.0 19.2 1.0

P.Filippakopoulos, S.Picaud, M.Mangos, T.Keates, J.P.Lambert, D.Barsyte-Lovejoy, I.Felletar, R.Volkmer, S.Muller, T.Pawson, A.C.Gingras, C.H.Arrowsmith, S.Knapp. Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family. Cell(Cambridge,Mass.) V. 149 214 2012.
ISSN: ISSN 0092-8674
PubMed: 22464331
DOI: 10.1016/J.CELL.2012.02.013