Sodium in the structure of Crystal Structure of Human Bromodomain Containing Protein 3 (BRD3) (pdb 2nxb)

The binding sites of Sodium atom in the structure of Crystal Structure of Human Bromodomain Containing Protein 3 (BRD3) (pdb code 2nxb). This binding sites where shown with 5.0 Angstroms radius around Sodium atom. The 2nxb structure was solved by P.FILIPPAKOPOULOS, A.BULLOCK, C.COOPER, K.KEATES, G.BERRIDGE, A.PIKE, G.BUNKOCZI, A.EDWARDS, C.ARROWSMITH, M.SUNDSTROM, F.VON DELFT, S.KNAPP, STRUCTURAL GENOMICS CONSORTIUM (SGC), with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 49.9-1.4 Space group P212121 a (A) 51.504 b (A) 61.840 c (A) 84.523 alpha (°) 90.00 beta (°) 90.00 gamma (°) 90.00 Rfactor (%) 16.8 Rfree (%) 18.5 Sodium Binding Sites: Sodium binding site 1 out of 1 in 2nxb Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Sodium in the PDB 2nxb. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Sodium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Thr36, A: Gln38, A: Leu39, A: Ser97, A: Ala98, A: Glu143, A: Hoh318, A: Hoh391, conact list: Atom Atom Distance (A) Na CB A:Thr36 3.58 Na CG2 A:Thr36 3.73 Na OG1 A:Thr36 2.86 Na N A:Gln38 4.81 Na OE1 A:Gln38 2.90 Na CB A:Gln38 3.65 Na CD A:Gln38 3.89 Na C A:Gln38 4.91 Na CG A:Gln38 4.25 Na CA A:Gln38 4.66 Na N A:Leu39 4.51 Na CD1 A:Leu39 4.75 Na CG A:Leu39 4.51 Na O A:Ser97 4.97 Na CB A:Ser97 4.09 Na OG A:Ser97 3.18 Na C A:Ser97 3.80 Na CA A:Ser97 3.75 Na N A:Ala98 2.95 Na CB A:Ala98 3.49 Na CA A:Ala98 3.80 Na OE2 A:Glu143 3.94 Na CD A:Glu143 4.59 Na CG A:Glu143 4.77 Na O A:Hoh318 4.21 Na O A:Hoh391 4.16 interactive model: