Atomistry » Sodium » PDB 2mat-2oj0 » 2nn1
Atomistry »
  Sodium »
    PDB 2mat-2oj0 »
      2nn1 »

Sodium in PDB 2nn1: Structure of Inhibitor Binding to Carbonic Anhydrase I

Enzymatic activity of Structure of Inhibitor Binding to Carbonic Anhydrase I

All present enzymatic activity of Structure of Inhibitor Binding to Carbonic Anhydrase I:
4.2.1.1;

Protein crystallography data

The structure of Structure of Inhibitor Binding to Carbonic Anhydrase I, PDB code: 2nn1 was solved by D.W.Christianson, K.M.Jude, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 28.63 / 1.65
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 62.421, 71.818, 121.965, 90.00, 90.00, 90.00
R / Rfree (%) 19.9 / 22.2

Other elements in 2nn1:

The structure of Structure of Inhibitor Binding to Carbonic Anhydrase I also contains other interesting chemical elements:

Zinc (Zn) 2 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the Structure of Inhibitor Binding to Carbonic Anhydrase I (pdb code 2nn1). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Structure of Inhibitor Binding to Carbonic Anhydrase I, PDB code: 2nn1:

Sodium binding site 1 out of 1 in 2nn1

Go back to Sodium Binding Sites List in 2nn1
Sodium binding site 1 out of 1 in the Structure of Inhibitor Binding to Carbonic Anhydrase I


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structure of Inhibitor Binding to Carbonic Anhydrase I within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Na351

b:32.8
occ:1.00
O B:SER259 2.3 20.8 1.0
O B:HOH469 2.3 19.1 1.0
O B:HOH468 2.4 26.9 1.0
O B:HOH688 2.5 25.2 1.0
O B:HOH548 2.6 26.7 1.0
O B:HOH665 2.6 29.9 1.0
C B:SER259 3.4 19.8 1.0
O B:LEU44 3.8 21.5 1.0
NE2 B:HIS40 3.8 21.0 1.0
CA B:SER259 4.0 18.1 1.0
O B:HOH471 4.3 23.3 1.0
CB B:SER259 4.3 17.1 1.0
N B:PHE260 4.5 19.9 1.0
O B:HOH559 4.6 25.0 1.0
O B:HOH905 4.6 40.8 1.0
CE1 B:HIS40 4.7 19.8 1.0
O B:HOH852 4.7 43.8 1.0
CD2 B:HIS40 4.7 19.9 1.0
CA B:PHE260 4.8 23.3 1.0
OG B:SER259 4.9 15.6 1.0
O B:ASP41 5.0 16.6 1.0
C B:LEU44 5.0 20.0 1.0

Reference:

D.K.Srivastava, K.M.Jude, A.L.Banerjee, M.Haldar, S.Manokaran, J.Kooren, S.Mallik, D.W.Christianson. Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II J.Am.Chem.Soc. V. 129 5528 2007.
ISSN: ISSN 0002-7863
PubMed: 17407288
DOI: 10.1021/JA068359W
Page generated: Tue Dec 15 05:52:04 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy