Sodium in the structure of Potassium Channel Kcsa-Fab Complex in Sodium Chloride (pdb 2itc)

The binding sites of Sodium atom in the structure of Potassium Channel Kcsa-Fab Complex in Sodium Chloride (pdb code 2itc). This binding sites where shown with 5.0 Angstroms radius around Sodium atom. The 2itc structure was solved by S.W.LOCKLESS, M.ZHOU, R.MACKINNON, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 42.8-3.2 Space group I4 a (A) 155.501 b (A) 155.501 c (A) 75.820 alpha (°) 90.00 beta (°) 90.00 gamma (°) 90.00 Rfactor (%) 24.6 Rfree (%) 26.5 Sodium Binding Sites: Sodium binding site 1 out of 2 in 2itc Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Sodium in the PDB 2itc. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Sodium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: Gly77, C: Tyr78, C: Gly79, conact list: Atom Atom Distance (A) Na O C:Gly77 2.51 Na C C:Gly77 3.42 Na CA C:Gly77 3.78 Na O C:Tyr78 4.52 Na N C:Tyr78 4.49 Na C C:Tyr78 4.46 Na CA C:Tyr78 4.74 Na N C:Gly79 4.78 interactive model: Sodium binding site 2 out of 2 in 2itc Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Sodium in the PDB 2itc. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Sodium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: Thr75, C: Hoh127, conact list: Atom Atom Distance (A) Na O C:Thr75 4.46 Na CB C:Thr75 4.28 Na CG2 C:Thr75 4.99 Na OG1 C:Thr75 3.28 Na O C:Hoh127 4.21 interactive model: