Sodium in PDB 2itc: Potassium Channel Kcsa-Fab Complex in Sodium Chloride

The structure of Potassium Channel Kcsa-Fab Complex in Sodium Chloride, PDB code: 2itc was solved by S.W.Lockless, M.Zhou, R.Mackinnon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.79 / 3.20
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	155.501, 155.501, 75.820, 90.00, 90.00, 90.00
R / Rfree (%)	24.6 / 26.5

The binding sites of Sodium atom in the Potassium Channel Kcsa-Fab Complex in Sodium Chloride (pdb code 2itc). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Potassium Channel Kcsa-Fab Complex in Sodium Chloride, PDB code: 2itc:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Potassium Channel Kcsa-Fab Complex in Sodium Chloride


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Potassium Channel Kcsa-Fab Complex in Sodium Chloride within 5.0Å range: probe atom residue distance (Å) B Occ C:Na125 b:80.7 occ:0.25 O C:GLY77 2.5 0.1 1.0 C C:GLY77 3.4 99.7 1.0 CA C:GLY77 3.8 90.4 1.0 C C:TYR78 4.5 64.7 1.0 N C:TYR78 4.5 85.0 1.0 O C:TYR78 4.5 59.2 1.0 CA C:TYR78 4.7 70.9 1.0 N C:GLY79 4.8 54.7 1.0

Sodium binding site 2 out of 2 in the Potassium Channel Kcsa-Fab Complex in Sodium Chloride


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Potassium Channel Kcsa-Fab Complex in Sodium Chloride within 5.0Å range: probe atom residue distance (Å) B Occ C:Na126 b:74.1 occ:0.25 OG1 C:THR75 3.3 86.0 1.0 O C:HOH127 4.2 70.5 0.2 CB C:THR75 4.3 71.7 1.0 O C:THR75 4.5 70.7 1.0 CG2 C:THR75 5.0 87.0 1.0

S.W.Lockless, M.Zhou, R.Mackinnon. Structural and Thermodynamic Properties of Selective Ion Binding in A K(+) Channel. Plos Biol. V. 5 E121 2007.
ISSN: ISSN 1544-9173
PubMed: 17472437
DOI: 10.1371/JOURNAL.PBIO.0050121