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Atomistry » Sodium » PDB 2htx-2isp » 2iso | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 2htx-2isp » 2iso » |
Sodium in PDB 2iso: Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene TriphosphateEnzymatic activity of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate
All present enzymatic activity of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate:
2.7.7.7; Protein crystallography data
The structure of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate, PDB code: 2iso
was solved by
C.A.Sucato,
T.G.Upton,
B.A.Kashemirov,
V.Martinek,
Y.Xiang,
W.A.Beard,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2iso:
The structure of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate
(pdb code 2iso). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate, PDB code: 2iso: Jump to Sodium binding site number: 1; 2; 3; Sodium binding site 1 out of 3 in 2isoGo back to Sodium Binding Sites List in 2iso
Sodium binding site 1 out
of 3 in the Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate
Mono view Stereo pair view
Sodium binding site 2 out of 3 in 2isoGo back to Sodium Binding Sites List in 2iso
Sodium binding site 2 out
of 3 in the Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate
Mono view Stereo pair view
Sodium binding site 3 out of 3 in 2isoGo back to Sodium Binding Sites List in 2iso
Sodium binding site 3 out
of 3 in the Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate
Mono view Stereo pair view
Reference:
C.A.Sucato,
T.G.Upton,
B.A.Kashemirov,
V.K.Batra,
V.Martinek,
Y.Xiang,
W.A.Beard,
L.C.Pedersen,
S.H.Wilson,
C.E.Mckenna,
J.Florian,
A.Warshel,
M.F.Goodman.
Modifying the Beta,Gamma Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of Dna Polymerase Beta. Biochemistry V. 46 461 2007.
Page generated: Mon Oct 7 02:54:22 2024
ISSN: ISSN 0006-2960 PubMed: 17209556 DOI: 10.1021/BI061517B |
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