Sodium in PDB 2ic0: Urate Oxidase Under 2.0 Mpa Pressure of Xenon

All present enzymatic activity of Urate Oxidase Under 2.0 Mpa Pressure of Xenon:
1.7.3.3;

The structure of Urate Oxidase Under 2.0 Mpa Pressure of Xenon, PDB code: 2ic0 was solved by N.Colloc'h, P.Retailleau, J.Sopkova-De Oliveira Santos, J.H.Abraini, T.Prange, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.84 / 1.78
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	80.502, 96.583, 106.005, 90.00, 90.00, 90.00
R / Rfree (%)	16.4 / 20.1

The structure of Urate Oxidase Under 2.0 Mpa Pressure of Xenon also contains other interesting chemical elements:

Xenon

(Xe)

1 atom

The binding sites of Sodium atom in the Urate Oxidase Under 2.0 Mpa Pressure of Xenon (pdb code 2ic0). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Urate Oxidase Under 2.0 Mpa Pressure of Xenon, PDB code: 2ic0:

Sodium binding site 1 out of 1 in the Urate Oxidase Under 2.0 Mpa Pressure of Xenon


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Urate Oxidase Under 2.0 Mpa Pressure of Xenon within 5.0Å range: probe atom residue distance (Å) B Occ A:Na650 b:22.5 occ:1.00 O A:ILE88 2.3 21.0 1.0 O A:ILE94 2.4 18.4 1.0 O A:TYR91 2.4 21.4 1.0 O A:HOH795 2.4 31.6 1.0 OE1 A:GLU136 2.7 30.5 1.0 O A:ASN92 3.2 26.3 1.0 C A:ILE88 3.3 20.7 1.0 C A:TYR91 3.5 21.8 1.0 C A:ILE94 3.5 18.5 1.0 C A:ASN92 3.6 24.7 1.0 CD A:GLU136 3.6 34.1 1.0 CA A:ILE88 3.8 20.0 1.0 CA A:ASN92 3.8 25.0 1.0 ND1 A:HIS95 4.1 26.1 1.0 N A:ILE94 4.1 19.7 1.0 N A:ASN92 4.1 23.2 1.0 OE2 A:GLU136 4.2 37.3 1.0 CB A:ILE88 4.2 20.4 1.0 CA A:ILE94 4.3 18.6 1.0 N A:HIS93 4.5 23.3 1.0 N A:HIS95 4.5 17.6 1.0 N A:GLU89 4.5 20.3 1.0 CE1 A:HIS95 4.5 26.6 1.0 CA A:HIS95 4.6 18.2 1.0 CG A:GLU136 4.7 29.9 1.0 CA A:TYR91 4.7 20.9 1.0 O A:PHE87 4.8 19.6 1.0 CB A:ILE94 4.8 18.6 1.0 N A:TYR91 4.8 20.1 1.0 C A:HIS93 4.9 21.4 1.0 CA A:GLU89 5.0 21.2 1.0

N.Colloc'h, J.Sopkova-De Oliveira Santos, P.Retailleau, B.Langlois D'estainto, B.Gallois, A.Brisson, J.J.Risso, M.Lemaire, J.H.Abraini. Protein Crystallography Under Xenon and Nitrous Oxide Pressure: Comparison with in Vivo Pharmacology Studies and Implications For the Mechanism of Inhaled Anesthetic Action Biophys.J. V. 92 217 2007.
ISSN: ISSN 0006-3495
PubMed: 17028130
DOI: 10.1529/BIOPHYSJ.106.093807