Sodium in PDB 2iba: Urate Oxidase From Aspergillus Flavus Complexed with Its Inhibitor 8- Azaxanthine

All present enzymatic activity of Urate Oxidase From Aspergillus Flavus Complexed with Its Inhibitor 8- Azaxanthine:
1.7.3.3;

The structure of Urate Oxidase From Aspergillus Flavus Complexed with Its Inhibitor 8- Azaxanthine, PDB code: 2iba was solved by N.Colloc'h, P.Retailleau, J.Sopkova-De Oliveira Santos, T.Prange, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.87 / 1.50
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	80.492, 96.041, 105.343, 90.00, 90.00, 90.00
R / Rfree (%)	17.6 / 19.7

The binding sites of Sodium atom in the Urate Oxidase From Aspergillus Flavus Complexed with Its Inhibitor 8- Azaxanthine (pdb code 2iba). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Urate Oxidase From Aspergillus Flavus Complexed with Its Inhibitor 8- Azaxanthine, PDB code: 2iba:

Sodium binding site 1 out of 1 in the Urate Oxidase From Aspergillus Flavus Complexed with Its Inhibitor 8- Azaxanthine


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Urate Oxidase From Aspergillus Flavus Complexed with Its Inhibitor 8- Azaxanthine within 5.0Å range: probe atom residue distance (Å) B Occ A:Na650 b:22.1 occ:1.00 O A:ILE88 2.3 21.4 1.0 O A:HOH802 2.3 34.6 1.0 O A:ILE94 2.4 19.1 1.0 O A:TYR91 2.5 21.4 1.0 OE1 A:GLU136 2.6 32.9 1.0 O A:ASN92 3.3 25.0 1.0 C A:ILE88 3.4 20.4 1.0 C A:ILE94 3.5 18.4 1.0 C A:TYR91 3.6 21.8 1.0 C A:ASN92 3.6 23.2 1.0 CD A:GLU136 3.7 33.5 1.0 CA A:ILE88 3.8 19.9 1.0 CA A:ASN92 3.9 24.4 1.0 N A:ILE94 4.1 19.5 1.0 ND1 A:HIS95 4.1 25.6 1.0 N A:ASN92 4.2 22.8 1.0 CB A:ILE88 4.2 19.9 1.0 OE2 A:GLU136 4.2 36.7 1.0 CA A:ILE94 4.3 18.6 1.0 N A:HIS93 4.4 22.0 1.0 N A:HIS95 4.5 17.8 1.0 N A:GLU89 4.5 20.5 1.0 CA A:HIS95 4.6 18.5 1.0 CE1 A:HIS95 4.6 26.9 1.0 O A:PHE87 4.7 18.2 1.0 CG A:GLU136 4.7 30.4 1.0 CA A:TYR91 4.8 21.2 1.0 CB A:ILE94 4.8 18.5 1.0 N A:TYR91 4.8 21.1 1.0 C A:HIS93 4.9 20.0 1.0 CA A:GLU89 5.0 21.6 1.0

N.Colloc'h, J.Sopkova-De Oliveira Santos, P.Retailleau, B.Langlois D'estainto, B.Gallois, A.Brisson, J.J.Risso, M.Lemaire, J.H.Abraini. Protein Crystallography Under Xenon and Nitrous Oxide Pressure: Comparison with in Vivo Pharmacology Studies and Implications For the Mechanism of Inhaled Anesthetic Action Biophys.J. V. 92 217 2007.
ISSN: ISSN 0006-3495
PubMed: 17028130
DOI: 10.1529/BIOPHYSJ.106.093807