Sodium in PDB 2i2r: Crystal Structure of the KCHIP1/KV4.3 T1 Complex

The structure of Crystal Structure of the KCHIP1/KV4.3 T1 Complex, PDB code: 2i2r was solved by F.Findeisen, M.Pioletti, D.L.Minor Jr., with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	91.29 / 3.35
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	93.151, 98.105, 97.783, 91.00, 112.56, 111.77
R / Rfree (%)	23.7 / 26.8

The structure of Crystal Structure of the KCHIP1/KV4.3 T1 Complex also contains other interesting chemical elements:

Calcium	(Ca)	16 atoms
Zinc	(Zn)	8 atoms

The binding sites of Sodium atom in the Crystal Structure of the KCHIP1/KV4.3 T1 Complex (pdb code 2i2r). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 4 binding sites of Sodium where determined in the Crystal Structure of the KCHIP1/KV4.3 T1 Complex, PDB code: 2i2r:
Jump to Sodium binding site number: 1; 2; 3; 4;

Sodium binding site 1 out of 4 in the Crystal Structure of the KCHIP1/KV4.3 T1 Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the KCHIP1/KV4.3 T1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ H:Na701 b:0.2 occ:1.00 O H:GLU43 3.2 0.5 1.0 O H:PHE48 3.3 0.5 1.0 O H:THR46 3.4 0.4 1.0 N I:ASN35 3.7 0.0 1.0 C H:ASN47 3.9 0.5 1.0 C H:PHE48 3.9 0.2 1.0 N H:PHE48 4.0 0.9 1.0 CA H:ASN47 4.2 0.8 1.0 O H:ASN47 4.2 0.7 1.0 C H:GLU43 4.4 0.3 1.0 C H:THR46 4.5 0.1 1.0 CA H:PHE48 4.6 0.2 1.0 N H:THR49 4.6 0.1 1.0 OE1 H:GLU43 4.8 0.3 1.0 ND2 M:ASN214 4.8 0.5 1.0 N H:ASN47 4.8 0.8 1.0 CG H:GLU43 4.8 0.9 1.0 CA H:THR49 4.9 1.0 1.0

Sodium binding site 2 out of 4 in the Crystal Structure of the KCHIP1/KV4.3 T1 Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of the KCHIP1/KV4.3 T1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ F:Na702 b:0.3 occ:1.00 O F:GLU43 2.8 0.6 1.0 O F:PHE48 3.2 0.5 1.0 O F:THR46 3.3 0.3 1.0 C F:PHE48 3.9 0.2 1.0 C F:GLU43 3.9 0.4 1.0 N F:PHE48 4.1 1.0 1.0 C F:ASN47 4.2 0.6 1.0 OE1 F:GLU43 4.3 0.2 1.0 CG F:GLU43 4.3 0.9 1.0 C F:THR46 4.4 0.1 1.0 CA F:ASN47 4.4 0.8 1.0 CA F:PHE48 4.6 0.3 1.0 N F:THR49 4.6 0.9 1.0 O F:ASN47 4.6 0.8 1.0 CA F:GLU43 4.6 0.5 1.0 CA F:THR49 4.8 1.0 1.0 CD F:GLU43 4.9 1.0 1.0 N F:ASN47 4.9 0.8 1.0 O F:ALA44 4.9 0.8 1.0 N F:ALA44 4.9 0.3 1.0

Sodium binding site 3 out of 4 in the Crystal Structure of the KCHIP1/KV4.3 T1 Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Crystal Structure of the KCHIP1/KV4.3 T1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ E:Na703 b:81.4 occ:1.00 O E:PHE48 3.3 0.6 1.0 O E:GLU43 3.5 0.6 1.0 O E:THR46 3.6 0.2 1.0 C E:ASN47 3.8 0.6 1.0 C E:PHE48 3.8 0.3 1.0 N E:PHE48 4.0 0.8 1.0 O E:ASN47 4.0 0.8 1.0 CA E:ASN47 4.1 0.8 1.0 N E:THR49 4.4 0.1 1.0 CA E:PHE48 4.5 0.2 1.0 C E:THR46 4.6 0.1 1.0 C E:GLU43 4.7 0.4 1.0 CA E:THR49 4.8 1.0 1.0 N E:ASN47 4.8 0.9 1.0 OE1 E:GLU43 4.8 0.3 1.0 CG2 E:THR49 4.9 0.9 1.0 CB L:ASN35 5.0 0.5 1.0

Sodium binding site 4 out of 4 in the Crystal Structure of the KCHIP1/KV4.3 T1 Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 4 of Crystal Structure of the KCHIP1/KV4.3 T1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ G:Na704 b:0.6 occ:1.00 O G:GLU43 2.5 0.6 1.0 O G:PHE48 2.9 0.6 1.0 O G:THR46 3.0 0.2 1.0 C G:GLU43 3.7 0.4 1.0 C G:PHE48 3.7 0.3 1.0 N G:PHE48 3.9 0.9 1.0 C G:ASN47 4.0 0.5 1.0 C G:THR46 4.1 0.1 1.0 CG G:GLU43 4.2 0.8 1.0 CA G:ASN47 4.3 0.9 1.0 OE1 G:GLU43 4.3 0.2 1.0 CA G:GLU43 4.3 0.6 1.0 CA G:PHE48 4.4 0.3 1.0 O G:ASN47 4.4 0.8 1.0 OD1 N:ASN214 4.4 0.0 1.0 N G:THR49 4.5 1.0 1.0 N G:ASN47 4.7 0.9 1.0 N G:ALA44 4.7 0.2 1.0 O G:ALA44 4.7 0.6 1.0 CA G:THR49 4.7 1.0 1.0 CD G:GLU43 4.8 0.8 1.0 CB G:GLU43 4.9 0.8 1.0 CA G:ALA44 4.9 1.0 1.0

M.Pioletti, F.Findeisen, G.L.Hura, D.L.Minor Jr.. Three-Dimensional Structure of the KCHIP1-KV4.3 T1 Complex Reveals A Cross-Shaped Octamer Nat.Struct.Mol.Biol. V. 13 987 2006.
ISSN: ISSN 1545-9993
PubMed: 17057713
DOI: 10.1038/NSMB1164