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Atomistry » Sodium » PDB 1s45-1t3p » 1so8 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 1s45-1t3p » 1so8 » |
Sodium in PDB 1so8: Abeta-Bound Human Abad Structure [Also Known As 3-Hydroxyacyl-Coa Dehydrogenase Type II (Type II Hadh), Endoplasmic Reticulum- Associated Amyloid Beta-Peptide Binding Protein (Erab)]Enzymatic activity of Abeta-Bound Human Abad Structure [Also Known As 3-Hydroxyacyl-Coa Dehydrogenase Type II (Type II Hadh), Endoplasmic Reticulum- Associated Amyloid Beta-Peptide Binding Protein (Erab)]
All present enzymatic activity of Abeta-Bound Human Abad Structure [Also Known As 3-Hydroxyacyl-Coa Dehydrogenase Type II (Type II Hadh), Endoplasmic Reticulum- Associated Amyloid Beta-Peptide Binding Protein (Erab)]:
1.1.1.35; Protein crystallography data
The structure of Abeta-Bound Human Abad Structure [Also Known As 3-Hydroxyacyl-Coa Dehydrogenase Type II (Type II Hadh), Endoplasmic Reticulum- Associated Amyloid Beta-Peptide Binding Protein (Erab)], PDB code: 1so8
was solved by
J.W.Lustbader,
M.Cirilli,
H.Wu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1so8:
The structure of Abeta-Bound Human Abad Structure [Also Known As 3-Hydroxyacyl-Coa Dehydrogenase Type II (Type II Hadh), Endoplasmic Reticulum- Associated Amyloid Beta-Peptide Binding Protein (Erab)] also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Abeta-Bound Human Abad Structure [Also Known As 3-Hydroxyacyl-Coa Dehydrogenase Type II (Type II Hadh), Endoplasmic Reticulum- Associated Amyloid Beta-Peptide Binding Protein (Erab)]
(pdb code 1so8). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Abeta-Bound Human Abad Structure [Also Known As 3-Hydroxyacyl-Coa Dehydrogenase Type II (Type II Hadh), Endoplasmic Reticulum- Associated Amyloid Beta-Peptide Binding Protein (Erab)], PDB code: 1so8: Jump to Sodium binding site number: 1; 2; Sodium binding site 1 out of 2 in 1so8Go back to Sodium Binding Sites List in 1so8
Sodium binding site 1 out
of 2 in the Abeta-Bound Human Abad Structure [Also Known As 3-Hydroxyacyl-Coa Dehydrogenase Type II (Type II Hadh), Endoplasmic Reticulum- Associated Amyloid Beta-Peptide Binding Protein (Erab)]
Mono view Stereo pair view
Sodium binding site 2 out of 2 in 1so8Go back to Sodium Binding Sites List in 1so8
Sodium binding site 2 out
of 2 in the Abeta-Bound Human Abad Structure [Also Known As 3-Hydroxyacyl-Coa Dehydrogenase Type II (Type II Hadh), Endoplasmic Reticulum- Associated Amyloid Beta-Peptide Binding Protein (Erab)]
Mono view Stereo pair view
Reference:
J.W.Lustbader,
M.Cirilli,
C.Lin,
H.W.Xu,
K.Takuma,
N.Wang,
C.Caspersen,
X.Chen,
S.Pollak,
M.Chaney,
F.Trinchese,
F.Gunn-Moore,
L.F.Lue,
D.G.Walker,
P.Kuppusamy,
Z.L.Zewier,
O.Arancio,
D.Stern,
S.S.Yan,
H.Wu.
Abad Directly Links Abeta to Mitochondrial Toxicity in Alzheimer'S Disease. Science V. 304 448 2004.
Page generated: Sun Oct 6 22:25:56 2024
ISSN: ISSN 0036-8075 PubMed: 15087549 DOI: 10.1126/SCIENCE.1091230 |
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