Sodium in PDB 1s5b: Cholera Holotoxin with An A-Subunit Y30S Mutation Form 3

All present enzymatic activity of Cholera Holotoxin with An A-Subunit Y30S Mutation Form 3:
2.4.2.36;

The structure of Cholera Holotoxin with An A-Subunit Y30S Mutation Form 3, PDB code: 1s5b was solved by C.J.O'neal, E.I.Amaya, M.G.Jobling, R.K.Holmes, W.G.Hol, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.02 / 2.13
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	60.104, 107.431, 65.950, 90.00, 91.29, 90.00
R / Rfree (%)	17.7 / 22.4

The binding sites of Sodium atom in the Cholera Holotoxin with An A-Subunit Y30S Mutation Form 3 (pdb code 1s5b). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Cholera Holotoxin with An A-Subunit Y30S Mutation Form 3, PDB code: 1s5b:

Sodium binding site 1 out of 1 in the Cholera Holotoxin with An A-Subunit Y30S Mutation Form 3


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Cholera Holotoxin with An A-Subunit Y30S Mutation Form 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na281 b:28.5 occ:1.00 O A:LEU153 2.2 15.1 1.0 O A:TYR150 2.3 16.2 1.0 OG1 A:THR90 2.4 16.3 1.0 O A:THR90 2.5 16.0 1.0 O A:HOH287 2.5 27.6 1.0 O A:ASN1 2.6 14.4 1.0 C A:LEU153 3.2 16.7 1.0 C A:THR90 3.3 17.9 1.0 CB A:THR90 3.4 17.3 1.0 N A:THR90 3.5 17.4 1.0 C A:TYR150 3.5 15.4 1.0 CA A:THR90 3.6 17.6 1.0 C A:ASN1 3.9 14.9 1.0 CA A:LEU153 4.0 17.1 1.0 N A:LEU153 4.1 16.7 1.0 N A:ASP154 4.1 16.3 1.0 CA A:SER151 4.2 16.1 1.0 CB A:LEU153 4.2 17.6 1.0 N A:ASN1 4.2 13.6 1.0 CA A:ASP154 4.3 17.3 1.0 N A:SER151 4.3 16.0 1.0 O A:HOH325 4.3 31.5 1.0 C A:SER151 4.4 16.1 1.0 N A:ALA91 4.4 18.1 1.0 CA A:TYR150 4.5 13.9 1.0 C A:ALA89 4.6 17.8 1.0 O A:SER151 4.6 16.7 1.0 O A:ASP3 4.6 16.6 1.0 CB A:ALA89 4.6 16.8 1.0 CG2 A:THR90 4.6 18.1 1.0 O A:HOH285 4.7 27.6 1.0 CA A:ASN1 4.7 13.6 1.0 N A:ASP2 4.8 15.6 1.0 CA A:ASP2 4.8 17.4 1.0 CB A:TYR150 4.8 14.0 1.0 OD1 A:ASP154 4.8 19.6 1.0 OD1 A:ASN1 4.9 14.8 1.0 N A:ASP3 4.9 16.7 1.0 CA A:ALA91 5.0 18.5 1.0 CA A:ALA89 5.0 16.9 1.0

C.J.O'neal, E.I.Amaya, M.G.Jobling, R.K.Holmes, W.G.Hol. Crystal Structures of An Intrinsically Active Cholera Toxin Mutant Yield Insight Into the Toxin Activation Mechanism Biochemistry V. 43 3772 2004.
ISSN: ISSN 0006-2960
PubMed: 15049684
DOI: 10.1021/BI0360152