Sodium in PDB 1nzw: CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+
Enzymatic activity of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+
All present enzymatic activity of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+:
1.2.1.3;
Protein crystallography data
The structure of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+, PDB code: 1nzw
was solved by
S.J.Perez-Miller,
T.D.Hurley,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
24.65 /
2.65
|
Space group
|
P 21 21 21
|
Cell size a, b, c (Å), α, β, γ (°)
|
141.361,
150.494,
176.923,
90.00,
90.00,
90.00
|
R / Rfree (%)
|
21.7 /
25.2
|
Other elements in 1nzw:
The structure of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+ also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+
(pdb code 1nzw). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 8 binding sites of Sodium where determined in the
CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+, PDB code: 1nzw:
Jump to Sodium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Sodium binding site 1 out
of 8 in 1nzw
Go back to
Sodium Binding Sites List in 1nzw
Sodium binding site 1 out
of 8 in the CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 1 of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na1601
b:31.2
occ:1.00
|
O
|
A:GLN196
|
2.3
|
34.1
|
1.0
|
OD1
|
A:ASP109
|
2.4
|
31.8
|
1.0
|
O
|
A:VAL40
|
2.4
|
39.0
|
1.0
|
O
|
A:ASP109
|
2.7
|
30.2
|
1.0
|
OG1
|
A:THR39
|
3.4
|
36.5
|
1.0
|
CG
|
A:ASP109
|
3.4
|
33.3
|
1.0
|
C
|
A:GLN196
|
3.5
|
32.6
|
1.0
|
C
|
A:VAL40
|
3.6
|
38.8
|
1.0
|
N
|
A:VAL40
|
3.7
|
39.2
|
1.0
|
C
|
A:ASP109
|
3.7
|
30.1
|
1.0
|
CA
|
A:ASP109
|
4.1
|
30.2
|
1.0
|
CA
|
A:VAL40
|
4.1
|
38.9
|
1.0
|
OD2
|
A:ASP109
|
4.2
|
34.7
|
1.0
|
CA
|
A:GLN196
|
4.2
|
32.9
|
1.0
|
CB
|
A:ASP109
|
4.4
|
31.8
|
1.0
|
CD
|
A:PRO42
|
4.4
|
36.3
|
1.0
|
C
|
A:THR39
|
4.4
|
39.2
|
1.0
|
N
|
A:THR197
|
4.5
|
31.4
|
1.0
|
CG2
|
A:THR197
|
4.6
|
26.2
|
1.0
|
CB
|
A:THR39
|
4.6
|
38.2
|
1.0
|
CB
|
A:GLN196
|
4.7
|
31.7
|
1.0
|
CA
|
A:THR197
|
4.7
|
29.9
|
1.0
|
N
|
A:ASN41
|
4.7
|
38.4
|
1.0
|
CA
|
A:THR39
|
4.7
|
38.1
|
1.0
|
O
|
A:VAL345
|
4.8
|
35.1
|
1.0
|
CB
|
A:VAL40
|
4.8
|
38.3
|
1.0
|
N
|
A:ASN110
|
4.9
|
29.5
|
1.0
|
|
Sodium binding site 2 out
of 8 in 1nzw
Go back to
Sodium Binding Sites List in 1nzw
Sodium binding site 2 out
of 8 in the CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 2 of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Na1602
b:41.9
occ:1.00
|
OD1
|
B:ASP109
|
2.2
|
30.5
|
1.0
|
O
|
B:GLN196
|
2.2
|
24.8
|
1.0
|
O
|
B:VAL40
|
2.5
|
34.8
|
1.0
|
O
|
B:HOH2582
|
2.5
|
35.6
|
1.0
|
OG1
|
B:THR39
|
2.8
|
33.0
|
1.0
|
O
|
B:ASP109
|
3.0
|
27.7
|
1.0
|
O
|
B:HOH2571
|
3.1
|
26.7
|
1.0
|
C
|
B:GLN196
|
3.4
|
27.7
|
1.0
|
CG
|
B:ASP109
|
3.4
|
30.8
|
1.0
|
N
|
B:VAL40
|
3.5
|
34.7
|
1.0
|
C
|
B:VAL40
|
3.6
|
33.5
|
1.0
|
C
|
B:ASP109
|
4.0
|
28.6
|
1.0
|
CA
|
B:VAL40
|
4.0
|
33.8
|
1.0
|
C
|
B:THR39
|
4.1
|
34.9
|
1.0
|
CB
|
B:THR39
|
4.1
|
34.9
|
1.0
|
CA
|
B:GLN196
|
4.2
|
28.5
|
1.0
|
CA
|
B:ASP109
|
4.2
|
27.8
|
1.0
|
OD2
|
B:ASP109
|
4.2
|
30.8
|
1.0
|
CA
|
B:THR39
|
4.3
|
34.6
|
1.0
|
CB
|
B:ASP109
|
4.4
|
28.6
|
1.0
|
N
|
B:THR197
|
4.4
|
28.4
|
1.0
|
CG2
|
B:THR197
|
4.6
|
32.1
|
1.0
|
CA
|
B:THR197
|
4.6
|
30.0
|
1.0
|
N
|
B:ASN41
|
4.7
|
31.8
|
1.0
|
CD
|
B:PRO42
|
4.8
|
31.4
|
1.0
|
CB
|
B:GLN196
|
4.8
|
25.6
|
1.0
|
CB
|
B:VAL40
|
4.8
|
33.0
|
1.0
|
O
|
B:THR39
|
4.9
|
32.5
|
1.0
|
CD1
|
B:ILE48
|
5.0
|
30.9
|
1.0
|
CG2
|
B:THR39
|
5.0
|
34.7
|
1.0
|
|
Sodium binding site 3 out
of 8 in 1nzw
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Sodium Binding Sites List in 1nzw
Sodium binding site 3 out
of 8 in the CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 3 of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Na1603
b:27.4
occ:1.00
|
O
|
C:HOH3549
|
2.1
|
26.0
|
1.0
|
O
|
C:VAL40
|
2.3
|
24.8
|
1.0
|
O
|
C:GLN196
|
2.4
|
22.5
|
1.0
|
OD1
|
C:ASP109
|
2.4
|
16.2
|
1.0
|
O
|
C:ASP109
|
2.8
|
17.9
|
1.0
|
OG1
|
C:THR39
|
3.4
|
26.4
|
1.0
|
C
|
C:VAL40
|
3.4
|
24.6
|
1.0
|
O
|
C:HOH3561
|
3.5
|
40.8
|
1.0
|
N
|
C:VAL40
|
3.5
|
23.9
|
1.0
|
C
|
C:GLN196
|
3.5
|
22.3
|
1.0
|
CG
|
C:ASP109
|
3.6
|
15.9
|
1.0
|
C
|
C:ASP109
|
3.9
|
16.7
|
1.0
|
CA
|
C:VAL40
|
3.9
|
24.7
|
1.0
|
CA
|
C:ASP109
|
4.2
|
17.3
|
1.0
|
CA
|
C:GLN196
|
4.3
|
21.7
|
1.0
|
CD
|
C:PRO42
|
4.3
|
21.6
|
1.0
|
C
|
C:THR39
|
4.3
|
23.8
|
1.0
|
OD2
|
C:ASP109
|
4.5
|
12.4
|
1.0
|
CB
|
C:ASP109
|
4.5
|
17.1
|
1.0
|
N
|
C:ASN41
|
4.5
|
24.1
|
1.0
|
CB
|
C:THR39
|
4.6
|
24.3
|
1.0
|
N
|
C:THR197
|
4.6
|
22.7
|
1.0
|
CG2
|
C:THR197
|
4.7
|
22.0
|
1.0
|
CA
|
C:THR39
|
4.7
|
23.7
|
1.0
|
CB
|
C:VAL40
|
4.7
|
25.9
|
1.0
|
CB
|
C:GLN196
|
4.7
|
22.1
|
1.0
|
O
|
C:VAL345
|
4.7
|
22.8
|
1.0
|
CA
|
C:THR197
|
4.8
|
21.3
|
1.0
|
CD1
|
C:ILE48
|
4.9
|
24.9
|
1.0
|
CA
|
C:ASN41
|
5.0
|
22.0
|
1.0
|
|
Sodium binding site 4 out
of 8 in 1nzw
Go back to
Sodium Binding Sites List in 1nzw
Sodium binding site 4 out
of 8 in the CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 4 of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Na1604
b:41.6
occ:1.00
|
O
|
D:VAL40
|
2.3
|
33.6
|
1.0
|
OD1
|
D:ASP109
|
2.4
|
34.4
|
1.0
|
O
|
D:GLN196
|
2.4
|
33.3
|
1.0
|
O
|
D:ASP109
|
2.5
|
29.8
|
1.0
|
OG1
|
D:THR39
|
3.3
|
32.7
|
1.0
|
C
|
D:VAL40
|
3.5
|
34.1
|
1.0
|
C
|
D:ASP109
|
3.6
|
30.9
|
1.0
|
CG
|
D:ASP109
|
3.6
|
35.0
|
1.0
|
C
|
D:GLN196
|
3.6
|
31.4
|
1.0
|
N
|
D:VAL40
|
3.7
|
34.1
|
1.0
|
CA
|
D:ASP109
|
4.0
|
30.6
|
1.0
|
CA
|
D:VAL40
|
4.1
|
34.7
|
1.0
|
CD
|
D:PRO42
|
4.3
|
35.6
|
1.0
|
CG2
|
D:THR197
|
4.3
|
30.8
|
1.0
|
CB
|
D:ASP109
|
4.4
|
32.0
|
1.0
|
CA
|
D:GLN196
|
4.4
|
30.8
|
1.0
|
C
|
D:THR39
|
4.5
|
33.3
|
1.0
|
OD2
|
D:ASP109
|
4.5
|
35.3
|
1.0
|
CD1
|
D:ILE48
|
4.6
|
34.8
|
1.0
|
N
|
D:ASN41
|
4.6
|
33.6
|
1.0
|
N
|
D:THR197
|
4.6
|
30.4
|
1.0
|
CB
|
D:THR39
|
4.6
|
32.6
|
1.0
|
O
|
D:VAL345
|
4.7
|
35.7
|
1.0
|
CA
|
D:THR197
|
4.7
|
30.4
|
1.0
|
N
|
D:ASN110
|
4.8
|
30.8
|
1.0
|
CB
|
D:GLN196
|
4.8
|
31.6
|
1.0
|
CA
|
D:THR39
|
4.8
|
33.5
|
1.0
|
CB
|
D:VAL40
|
4.9
|
34.7
|
1.0
|
CA
|
D:ASN41
|
4.9
|
34.8
|
1.0
|
|
Sodium binding site 5 out
of 8 in 1nzw
Go back to
Sodium Binding Sites List in 1nzw
Sodium binding site 5 out
of 8 in the CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 5 of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Na1605
b:40.3
occ:1.00
|
O
|
E:GLN196
|
2.3
|
32.2
|
1.0
|
O
|
E:ASP109
|
2.4
|
30.0
|
1.0
|
OD1
|
E:ASP109
|
2.4
|
30.1
|
1.0
|
O
|
E:VAL40
|
2.7
|
34.7
|
1.0
|
C
|
E:GLN196
|
3.4
|
32.4
|
1.0
|
OG1
|
E:THR39
|
3.5
|
29.9
|
1.0
|
C
|
E:ASP109
|
3.5
|
32.0
|
1.0
|
CG
|
E:ASP109
|
3.5
|
30.1
|
1.0
|
C
|
E:VAL40
|
3.8
|
33.8
|
1.0
|
CA
|
E:ASP109
|
4.0
|
32.2
|
1.0
|
N
|
E:VAL40
|
4.1
|
33.2
|
1.0
|
CG2
|
E:THR197
|
4.2
|
34.9
|
1.0
|
CA
|
E:GLN196
|
4.2
|
32.2
|
1.0
|
CD
|
E:PRO42
|
4.3
|
36.2
|
1.0
|
CB
|
E:ASP109
|
4.3
|
31.7
|
1.0
|
OD2
|
E:ASP109
|
4.4
|
32.1
|
1.0
|
N
|
E:THR197
|
4.4
|
32.5
|
1.0
|
O
|
E:VAL345
|
4.5
|
32.7
|
1.0
|
CA
|
E:VAL40
|
4.5
|
33.6
|
1.0
|
CA
|
E:THR197
|
4.6
|
32.3
|
1.0
|
CB
|
E:GLN196
|
4.6
|
31.2
|
1.0
|
N
|
E:ASN110
|
4.6
|
32.1
|
1.0
|
CB
|
E:THR39
|
4.8
|
33.9
|
1.0
|
C
|
E:THR39
|
4.8
|
33.9
|
1.0
|
CG2
|
E:VAL345
|
4.9
|
28.4
|
1.0
|
N
|
E:ASN41
|
4.9
|
33.8
|
1.0
|
|
Sodium binding site 6 out
of 8 in 1nzw
Go back to
Sodium Binding Sites List in 1nzw
Sodium binding site 6 out
of 8 in the CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 6 of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Na1606
b:27.6
occ:1.00
|
O
|
F:GLN196
|
2.3
|
22.8
|
1.0
|
O
|
F:VAL40
|
2.4
|
25.6
|
1.0
|
OD1
|
F:ASP109
|
2.5
|
23.9
|
1.0
|
O
|
F:ASP109
|
2.7
|
21.9
|
1.0
|
OG1
|
F:THR39
|
3.4
|
24.1
|
1.0
|
C
|
F:GLN196
|
3.5
|
21.1
|
1.0
|
C
|
F:VAL40
|
3.5
|
25.9
|
1.0
|
CG
|
F:ASP109
|
3.7
|
22.7
|
1.0
|
C
|
F:ASP109
|
3.7
|
21.3
|
1.0
|
N
|
F:VAL40
|
3.8
|
25.5
|
1.0
|
CA
|
F:VAL40
|
4.1
|
25.3
|
1.0
|
CA
|
F:ASP109
|
4.2
|
20.3
|
1.0
|
CA
|
F:GLN196
|
4.2
|
19.7
|
1.0
|
CD
|
F:PRO42
|
4.3
|
22.8
|
1.0
|
CG2
|
F:THR197
|
4.5
|
16.6
|
1.0
|
O
|
F:VAL345
|
4.5
|
28.1
|
1.0
|
CB
|
F:ASP109
|
4.5
|
21.5
|
1.0
|
C
|
F:THR39
|
4.5
|
24.0
|
1.0
|
N
|
F:THR197
|
4.5
|
20.9
|
1.0
|
CB
|
F:GLN196
|
4.5
|
21.8
|
1.0
|
OD2
|
F:ASP109
|
4.5
|
20.8
|
1.0
|
O
|
F:HOH6593
|
4.6
|
31.6
|
1.0
|
N
|
F:ASN41
|
4.7
|
26.2
|
1.0
|
CB
|
F:THR39
|
4.7
|
22.6
|
1.0
|
CA
|
F:THR197
|
4.8
|
18.4
|
1.0
|
CA
|
F:THR39
|
4.8
|
22.6
|
1.0
|
CB
|
F:VAL40
|
4.9
|
23.9
|
1.0
|
N
|
F:ASN110
|
4.9
|
19.8
|
1.0
|
|
Sodium binding site 7 out
of 8 in 1nzw
Go back to
Sodium Binding Sites List in 1nzw
Sodium binding site 7 out
of 8 in the CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 7 of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Na1607
b:34.9
occ:1.00
|
O
|
G:VAL40
|
2.3
|
30.9
|
1.0
|
OD1
|
G:ASP109
|
2.4
|
23.2
|
1.0
|
O
|
G:GLN196
|
2.4
|
29.5
|
1.0
|
O
|
G:ASP109
|
2.5
|
25.5
|
1.0
|
OG1
|
G:THR39
|
3.3
|
35.0
|
1.0
|
C
|
G:VAL40
|
3.4
|
31.9
|
1.0
|
CG
|
G:ASP109
|
3.5
|
22.9
|
1.0
|
C
|
G:ASP109
|
3.6
|
26.5
|
1.0
|
C
|
G:GLN196
|
3.6
|
30.5
|
1.0
|
N
|
G:VAL40
|
3.7
|
33.7
|
1.0
|
CA
|
G:ASP109
|
3.9
|
25.6
|
1.0
|
CA
|
G:VAL40
|
4.1
|
32.4
|
1.0
|
CD
|
G:PRO42
|
4.2
|
28.5
|
1.0
|
CB
|
G:ASP109
|
4.3
|
24.1
|
1.0
|
OD2
|
G:ASP109
|
4.4
|
22.2
|
1.0
|
C
|
G:THR39
|
4.4
|
33.9
|
1.0
|
CG2
|
G:THR197
|
4.4
|
29.5
|
1.0
|
CA
|
G:GLN196
|
4.5
|
29.8
|
1.0
|
N
|
G:ASN41
|
4.5
|
29.9
|
1.0
|
CB
|
G:THR39
|
4.6
|
34.2
|
1.0
|
CD1
|
G:ILE48
|
4.6
|
34.3
|
1.0
|
N
|
G:THR197
|
4.6
|
30.9
|
1.0
|
CA
|
G:THR197
|
4.7
|
30.1
|
1.0
|
CA
|
G:THR39
|
4.8
|
33.7
|
1.0
|
N
|
G:ASN110
|
4.8
|
28.5
|
1.0
|
CB
|
G:VAL40
|
4.8
|
32.0
|
1.0
|
O
|
G:VAL345
|
4.8
|
30.3
|
1.0
|
CA
|
G:ASN41
|
4.9
|
30.2
|
1.0
|
CB
|
G:GLN196
|
4.9
|
29.0
|
1.0
|
|
Sodium binding site 8 out
of 8 in 1nzw
Go back to
Sodium Binding Sites List in 1nzw
Sodium binding site 8 out
of 8 in the CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 8 of CYS302SER Mutant of Human Mitochondrial Aldehyde Dehydrogenase Complexed with Nadh and MG2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Na1608
b:34.5
occ:1.00
|
O
|
H:GLN196
|
2.3
|
36.4
|
1.0
|
OD1
|
H:ASP109
|
2.4
|
35.1
|
1.0
|
O
|
H:VAL40
|
2.5
|
41.4
|
1.0
|
O
|
H:ASP109
|
2.6
|
29.3
|
1.0
|
O
|
H:HOH8543
|
3.1
|
28.2
|
1.0
|
C
|
H:GLN196
|
3.5
|
34.1
|
1.0
|
OG1
|
H:THR39
|
3.5
|
38.4
|
1.0
|
CG
|
H:ASP109
|
3.6
|
34.6
|
1.0
|
C
|
H:VAL40
|
3.6
|
39.4
|
1.0
|
C
|
H:ASP109
|
3.7
|
30.8
|
1.0
|
N
|
H:VAL40
|
3.9
|
38.4
|
1.0
|
CA
|
H:ASP109
|
4.1
|
31.6
|
1.0
|
CA
|
H:GLN196
|
4.2
|
32.8
|
1.0
|
CA
|
H:VAL40
|
4.3
|
38.8
|
1.0
|
CD
|
H:PRO42
|
4.3
|
38.8
|
1.0
|
CB
|
H:ASP109
|
4.5
|
32.8
|
1.0
|
O
|
H:VAL345
|
4.5
|
37.2
|
1.0
|
CG2
|
H:THR197
|
4.5
|
31.8
|
1.0
|
OD2
|
H:ASP109
|
4.5
|
35.1
|
1.0
|
N
|
H:THR197
|
4.5
|
34.3
|
1.0
|
CB
|
H:GLN196
|
4.6
|
29.8
|
1.0
|
C
|
H:THR39
|
4.6
|
38.1
|
1.0
|
CA
|
H:THR197
|
4.7
|
33.3
|
1.0
|
N
|
H:ASN41
|
4.8
|
38.4
|
1.0
|
CB
|
H:THR39
|
4.8
|
37.9
|
1.0
|
N
|
H:ASN110
|
4.8
|
30.6
|
1.0
|
CA
|
H:THR39
|
4.9
|
37.8
|
1.0
|
CG2
|
H:VAL345
|
4.9
|
34.4
|
1.0
|
CB
|
H:VAL40
|
4.9
|
38.7
|
1.0
|
|
Reference:
S.J.Perez-Miller,
T.D.Hurley.
Coenzyme Isomerization Is Integral to Catalysis in Aldehyde Dehydrogenase Biochemistry V. 42 7100 2003.
ISSN: ISSN 0006-2960
PubMed: 12795606
DOI: 10.1021/BI034182W
Page generated: Sun Oct 6 21:01:24 2024
|