Sodium in PDB 1jmo: Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex

All present enzymatic activity of Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex:
3.4.21.5;

The structure of Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex, PDB code: 1jmo was solved by T.P.Baglin, R.W.Carrell, C.T.Esmon, J.A.Huntington, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.44 / 2.20
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	152.310, 152.310, 126.800, 90.00, 90.00, 120.00
R / Rfree (%)	20.5 / 21.1

The binding sites of Sodium atom in the Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex (pdb code 1jmo). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex, PDB code: 1jmo:

Sodium binding site 1 out of 1 in the Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex within 5.0Å range: probe atom residue distance (Å) B Occ H:Na501 b:67.1 occ:1.00 O H:LYS224 2.6 42.3 1.0 O H:HOH2048 2.9 53.6 1.0 O H:HOH2082 3.1 56.8 1.0 O H:TYR184A 3.1 46.5 1.0 O H:HOH2061 3.2 44.9 1.0 O H:HOH2086 3.6 60.0 1.0 CD2 H:TYR225 3.7 46.9 1.0 N H:TYR184A 3.7 44.5 1.0 C H:LYS224 3.8 42.9 1.0 CE2 H:TYR225 4.0 48.9 1.0 CA H:GLY184 4.0 41.1 1.0 C H:GLY184 4.0 43.0 1.0 O H:ARG221A 4.1 52.8 1.0 C H:TYR184A 4.1 46.9 1.0 CA H:TYR225 4.3 43.4 1.0 CG H:TYR225 4.5 46.5 1.0 CA H:TYR184A 4.5 45.6 1.0 N H:TYR225 4.6 42.4 1.0 N H:LYS224 4.7 45.3 1.0 CB H:TYR225 4.9 44.2 1.0 O H:GLY184 4.9 44.0 1.0 O H:GLY188 4.9 42.3 1.0 CZ H:TYR225 4.9 49.5 1.0 CA H:LYS224 4.9 44.5 1.0

T.P.Baglin, R.W.Carrell, F.C.Church, C.T.Esmon, J.A.Huntington. Crystal Structures of Native and Thrombin-Complexed Heparin Cofactor II Reveal A Multistep Allosteric Mechanism. Proc.Natl.Acad.Sci.Usa V. 99 11079 2002.
ISSN: ISSN 0027-8424
PubMed: 12169660
DOI: 10.1073/PNAS.162232399