Sodium in PDB 7okw: 1.62A X-Ray Crystal Structure of the Conserved C-Terminal (Cct) of Human OSR1

All present enzymatic activity of 1.62A X-Ray Crystal Structure of the Conserved C-Terminal (Cct) of Human OSR1:
2.7.11.1;

The structure of 1.62A X-Ray Crystal Structure of the Conserved C-Terminal (Cct) of Human OSR1, PDB code: 7okw was solved by B.D.Bax, K.T.Elvers, M.Lipka-Lloyd, Y.Mehellou, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.61 / 1.62
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	70.168, 49.424, 56.439, 90, 99.44, 90
R / Rfree (%)	18.4 / 21.7

The structure of 1.62A X-Ray Crystal Structure of the Conserved C-Terminal (Cct) of Human OSR1 also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Calcium	(Ca)	1 atom

The binding sites of Sodium atom in the 1.62A X-Ray Crystal Structure of the Conserved C-Terminal (Cct) of Human OSR1 (pdb code 7okw). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the 1.62A X-Ray Crystal Structure of the Conserved C-Terminal (Cct) of Human OSR1, PDB code: 7okw:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the 1.62A X-Ray Crystal Structure of the Conserved C-Terminal (Cct) of Human OSR1


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of 1.62A X-Ray Crystal Structure of the Conserved C-Terminal (Cct) of Human OSR1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na604 b:49.8 occ:1.00 O A:HOH727 2.3 33.1 1.0 OG A:SER510 2.3 33.6 1.0 OD1 A:ASP511 3.4 35.1 1.0 CB A:SER510 3.7 27.2 1.0 NZ A:LYS445 3.9 51.7 1.0 N A:ASP511 4.3 22.5 1.0 C A:SER510 4.3 26.4 1.0 CA A:SER510 4.4 28.6 1.0 CE A:LYS445 4.4 43.1 1.0 CG A:ASP511 4.4 35.9 1.0 N A:SER510 4.5 31.2 1.0 O A:SER510 4.8 21.9 1.0 CA A:ASP511 4.9 26.1 1.0 O A:HOH761 4.9 38.6 1.0

Sodium binding site 2 out of 2 in the 1.62A X-Ray Crystal Structure of the Conserved C-Terminal (Cct) of Human OSR1


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of 1.62A X-Ray Crystal Structure of the Conserved C-Terminal (Cct) of Human OSR1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Na603 b:42.0 occ:1.00 O B:HOH712 2.3 41.2 1.0 O A:HOH756 2.6 33.8 1.0 OD1 B:ASP515 2.9 31.9 1.0 O B:HOH759 3.7 32.0 1.0 CG B:ASP515 3.8 26.4 1.0 OD2 B:ASP515 3.9 26.3 1.0 OXT A:SER527 4.0 35.3 1.0 O A:SER527 4.2 42.1 1.0 NH2 A:ARG497 4.4 23.7 1.0 C A:SER527 4.5 32.3 1.0 OD1 B:ASP514 4.5 32.8 1.0 N B:ASP515 4.9 20.9 1.0 N B:GLY516 5.0 19.1 1.0

B.D.Bax, K.T.Elvers, M.Lipka-Lloyd, Y.Mehellou, R.Trueman. Crystal Structures of the Human Spak and OSR1 Conserved C-Terminal Domains To Be Published.