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Sodium in PDB 8xb0: Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with Sam and Compound 292Enzymatic activity of Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with Sam and Compound 292
All present enzymatic activity of Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with Sam and Compound 292:
2.5.1.6; Protein crystallography data
The structure of Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with Sam and Compound 292, PDB code: 8xb0
was solved by
S.L.Tong,
G.P.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8xb0:
The structure of Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with Sam and Compound 292 also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with Sam and Compound 292
(pdb code 8xb0). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with Sam and Compound 292, PDB code: 8xb0: Sodium binding site 1 out of 1 in 8xb0Go back to Sodium Binding Sites List in 8xb0
Sodium binding site 1 out
of 1 in the Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with Sam and Compound 292
Mono view Stereo pair view
Reference:
J.Zheng,
T.Zhang,
S.Tong,
T.Liu,
J.Cui,
H.Xu,
D.Hu,
Y.Shen,
Y.Yin,
D.Zhao,
C.Tan,
X.Dong,
J.Chen,
F.Ji,
C.Tong,
J.J.Li,
J.Li,
G.Zhang.
Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and in Vivo Efficacy. J.Med.Chem. V. 67 9431 2024.
Page generated: Wed Oct 9 14:21:30 2024
ISSN: ISSN 0022-2623 PubMed: 38818879 DOI: 10.1021/ACS.JMEDCHEM.4C00552 |
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