Sodium in PDB 8v6m: Inactivated-State Cryo-Em Structure of Human TRPV3 in Presence of Tetrahydrocannabivarin (Thcv) in CNW30 Nanodiscs

The binding sites of Sodium atom in the Inactivated-State Cryo-Em Structure of Human TRPV3 in Presence of Tetrahydrocannabivarin (Thcv) in CNW30 Nanodiscs (pdb code 8v6m). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Inactivated-State Cryo-Em Structure of Human TRPV3 in Presence of Tetrahydrocannabivarin (Thcv) in CNW30 Nanodiscs, PDB code: 8v6m:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the Inactivated-State Cryo-Em Structure of Human TRPV3 in Presence of Tetrahydrocannabivarin (Thcv) in CNW30 Nanodiscs


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Inactivated-State Cryo-Em Structure of Human TRPV3 in Presence of Tetrahydrocannabivarin (Thcv) in CNW30 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ A:Na905 b:44.5 occ:1.00 O A:GLY638 2.5 37.3 1.0 O D:GLY638 2.5 46.0 1.0 O C:GLY638 2.5 35.7 1.0 O B:GLY638 2.5 36.9 1.0 HA A:LEU639 3.4 37.5 1.0 C A:GLY638 3.4 37.3 1.0 HA D:LEU639 3.4 46.0 1.0 C C:GLY638 3.4 35.7 1.0 HA C:LEU639 3.4 36.4 1.0 C D:GLY638 3.4 46.0 1.0 HA B:LEU639 3.5 37.1 1.0 C B:GLY638 3.5 36.9 1.0 N A:LEU639 4.1 37.5 1.0 N C:LEU639 4.1 36.4 1.0 N D:LEU639 4.1 46.0 1.0 N B:LEU639 4.1 37.1 1.0 CA A:LEU639 4.2 37.5 1.0 CA C:LEU639 4.2 36.4 1.0 CA D:LEU639 4.2 46.0 1.0 CA B:LEU639 4.2 37.1 1.0 HA3 C:GLY638 4.3 35.7 1.0 HA3 D:GLY638 4.3 46.0 1.0 HA3 A:GLY638 4.3 37.3 1.0 HA3 B:GLY638 4.3 36.9 1.0 CA C:GLY638 4.4 35.7 1.0 CA D:GLY638 4.4 46.0 1.0 CA A:GLY638 4.4 37.3 1.0 CA B:GLY638 4.4 36.9 1.0 HA2 C:GLY638 4.5 35.7 1.0 HA2 D:GLY638 4.5 46.0 1.0 HA2 A:GLY638 4.5 37.3 1.0 HA2 B:GLY638 4.6 36.9 1.0 H A:GLY640 4.7 42.6 1.0 H D:GLY640 4.7 51.6 1.0 H C:GLY640 4.7 40.9 1.0 H B:GLY640 4.7 41.7 1.0 H A:LEU639 4.8 37.5 1.0 H C:LEU639 4.8 36.4 1.0 H D:LEU639 4.8 46.0 1.0 H B:LEU639 4.9 37.1 1.0

Sodium binding site 2 out of 3 in the Inactivated-State Cryo-Em Structure of Human TRPV3 in Presence of Tetrahydrocannabivarin (Thcv) in CNW30 Nanodiscs


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Inactivated-State Cryo-Em Structure of Human TRPV3 in Presence of Tetrahydrocannabivarin (Thcv) in CNW30 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ A:Na906 b:44.5 occ:1.00 HA3 A:GLY638 3.8 37.3 1.0 HA3 D:GLY638 3.9 46.0 1.0 HA3 C:GLY638 3.9 35.7 1.0 HA3 B:GLY638 3.9 36.9 1.0 O A:ILE637 4.6 37.5 1.0 O D:ILE637 4.6 46.0 1.0 O C:ILE637 4.6 35.6 1.0 O B:ILE637 4.6 37.1 1.0 CA A:GLY638 4.8 37.3 1.0 CA D:GLY638 4.8 46.0 1.0 CA C:GLY638 4.8 35.7 1.0 CA B:GLY638 4.8 36.9 1.0

Sodium binding site 3 out of 3 in the Inactivated-State Cryo-Em Structure of Human TRPV3 in Presence of Tetrahydrocannabivarin (Thcv) in CNW30 Nanodiscs


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Inactivated-State Cryo-Em Structure of Human TRPV3 in Presence of Tetrahydrocannabivarin (Thcv) in CNW30 Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ A:Na907 b:44.5 occ:1.00 HE2 C:MET677 3.3 51.1 1.0 HE2 D:MET677 3.3 63.3 1.0 HE2 A:MET677 3.3 54.5 1.0 HE2 B:MET677 3.3 52.6 1.0 HE1 A:MET677 3.6 54.5 1.0 HE1 C:MET677 3.6 51.1 1.0 HE1 D:MET677 3.6 63.3 1.0 HE1 B:MET677 3.6 52.6 1.0 HE3 C:MET677 3.7 51.1 1.0 HE3 A:MET677 3.7 54.5 1.0 HE3 D:MET677 3.7 63.3 1.0 CE A:MET677 3.7 54.5 1.0 CE C:MET677 3.7 51.1 1.0 HE3 B:MET677 3.7 52.6 1.0 CE D:MET677 3.7 63.3 1.0 CE B:MET677 3.7 52.6 1.0 HB3 A:LEU673 4.0 46.0 1.0 HB3 D:LEU673 4.0 53.8 1.0 HB3 C:LEU673 4.0 43.6 1.0 HB3 B:LEU673 4.0 44.4 1.0 HD12 A:LEU673 4.4 46.0 1.0 HD12 D:LEU673 4.4 53.8 1.0 HD12 C:LEU673 4.4 43.6 1.0 HD12 B:LEU673 4.4 44.4 1.0 HG A:LEU673 4.4 46.0 1.0 HG D:LEU673 4.5 53.8 1.0 HG C:LEU673 4.5 43.6 1.0 HG B:LEU673 4.5 44.4 1.0 CB A:LEU673 4.9 46.0 1.0 CB D:LEU673 4.9 53.8 1.0 CB C:LEU673 4.9 43.6 1.0 CB B:LEU673 4.9 44.4 1.0

K.D.Nadezhdin, A.I.Sobolevsky. TRPV3 Activation By Different Agonists Accompanied By Lipid Dissociation From the Vanilloid Site To Be Published.