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Sodium in PDB 8uqa: Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker

Enzymatic activity of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker

All present enzymatic activity of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker:
2.3.2.23; 2.3.2.24; 2.3.2.27;

Protein crystallography data

The structure of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker, PDB code: 8uqa was solved by Q.Hu, M.V.Botuyan, G.Mer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.18 / 2.05
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 102.953, 102.953, 87.231, 90, 90, 120
R / Rfree (%) 19.2 / 23.1

Other elements in 8uqa:

The structure of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker also contains other interesting chemical elements:

Chlorine (Cl) 4 atoms
Zinc (Zn) 2 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker (pdb code 8uqa). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker, PDB code: 8uqa:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in 8uqa

Go back to Sodium Binding Sites List in 8uqa
Sodium binding site 1 out of 3 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker within 5.0Å range:
probe atom residue distance (Å) B Occ
K:Na4001

b:75.5
occ:1.00
O K:ILE22 2.3 62.2 1.0
O K:HOH5241 2.4 60.5 1.0
C K:ILE22 3.5 68.8 1.0
CG1 K:VAL24 3.6 83.5 1.0
CB K:GLU21 3.6 78.0 1.0
N K:VAL24 3.8 63.6 1.0
SG K:CYS19 4.1 74.9 1.0
CA K:LEU23 4.1 68.8 1.0
C K:LEU23 4.1 66.7 1.0
CG2 K:VAL24 4.1 64.7 1.0
CB K:CYS36 4.2 60.4 1.0
N K:LEU23 4.3 73.9 1.0
CB K:VAL24 4.3 70.9 1.0
N K:ILE22 4.3 76.5 1.0
SG K:CYS36 4.3 69.8 1.0
C K:GLU21 4.4 80.1 1.0
CA K:ILE22 4.5 74.1 1.0
CG K:GLU21 4.6 84.5 1.0
CG2 K:ILE22 4.6 73.4 0.0
CA K:GLU21 4.6 85.7 1.0
CA K:VAL24 4.7 73.6 1.0
O K:GLU21 4.7 85.4 1.0
O K:LEU23 4.9 73.4 1.0
CB K:CYS16 5.0 62.8 1.0

Sodium binding site 2 out of 3 in 8uqa

Go back to Sodium Binding Sites List in 8uqa
Sodium binding site 2 out of 3 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker within 5.0Å range:
probe atom residue distance (Å) B Occ
K:Na4002

b:48.0
occ:1.00
OE1 K:GLU13 2.3 66.5 1.0
CD K:GLU13 3.2 59.3 1.0
OE2 K:GLU13 3.8 60.5 0.0
CG K:GLU13 4.4 68.6 0.0
CB K:GLU13 5.0 73.9 0.0

Sodium binding site 3 out of 3 in 8uqa

Go back to Sodium Binding Sites List in 8uqa
Sodium binding site 3 out of 3 in the Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12- Residue Linker within 5.0Å range:
probe atom residue distance (Å) B Occ
K:Na4009

b:45.5
occ:1.00
O K:GLY1153 2.2 67.0 1.0
OD1 K:ASN3038 2.3 28.9 1.0
O K:HOH5077 2.4 36.8 1.0
O K:HOH5083 2.5 44.9 1.0
O K:HOH5157 2.7 51.9 1.0
OG K:SER1152 2.7 44.1 1.0
CG K:ASN3038 3.3 35.4 1.0
C K:GLY1153 3.4 70.4 1.0
ND2 K:ASN3038 3.6 35.1 1.0
N K:GLY1153 3.7 70.7 1.0
C K:SER1152 3.8 69.8 1.0
CB K:SER1152 3.9 49.9 1.0
O K:HOH5193 3.9 41.1 1.0
CA K:GLY1153 4.1 61.1 1.0
O K:LYS3036 4.2 28.3 1.0
O K:SER1152 4.2 62.5 1.0
CA K:SER1152 4.2 66.1 1.0
N K:SER1152 4.3 67.1 1.0
C K:GLY1154 4.3 60.0 1.0
O K:GLY1154 4.3 56.2 1.0
NE2 K:GLN1034 4.4 29.6 1.0
N K:GLY1156 4.4 40.4 1.0
N K:GLY1154 4.4 62.8 1.0
O K:ARG3035 4.5 28.9 1.0
N K:SER1155 4.6 53.1 1.0
CB K:ASN3038 4.7 25.6 1.0
CA K:GLY1154 4.7 65.7 1.0
C K:LYS3036 4.9 29.3 1.0

Reference:

Q.Hu, M.V.Botuyan, G.Mer. Crystal Structure of RNF168 (Ring)-UBCH5C Fused to H2A-H2B Via A 12-Residue Linker To Be Published.
Page generated: Wed Oct 9 13:54:19 2024

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