Sodium in PDB 8tz3: Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction
Sodium Binding Sites:
The binding sites of Sodium atom in the Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction
(pdb code 8tz3). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 6 binding sites of Sodium where determined in the
Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction, PDB code: 8tz3:
Jump to Sodium binding site number:
1;
2;
3;
4;
5;
6;
Sodium binding site 1 out
of 6 in 8tz3
Go back to
Sodium Binding Sites List in 8tz3
Sodium binding site 1 out
of 6 in the Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 1 of Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na801
b:18.0
occ:1.00
|
O
|
A:HOH902
|
2.3
|
18.6
|
1.0
|
|
OG1
|
A:THR376
|
2.4
|
18.0
|
1.0
|
|
OD1
|
A:ASN342
|
2.4
|
19.2
|
1.0
|
|
O
|
A:ASN342
|
2.5
|
19.2
|
1.0
|
|
O
|
A:ILE377
|
2.5
|
18.9
|
1.0
|
|
O
|
A:ILE345
|
2.5
|
21.3
|
1.0
|
|
HB
|
A:THR376
|
3.1
|
18.0
|
1.0
|
|
HG1
|
A:THR376
|
3.1
|
18.0
|
1.0
|
|
HA
|
A:ASN342
|
3.1
|
19.2
|
1.0
|
|
HB3
|
A:ASN342
|
3.2
|
19.2
|
1.0
|
|
HA2
|
A:GLY346
|
3.2
|
21.4
|
1.0
|
|
CB
|
A:THR376
|
3.3
|
18.0
|
1.0
|
|
CG
|
A:ASN342
|
3.3
|
19.2
|
1.0
|
|
C
|
A:ASN342
|
3.3
|
19.2
|
1.0
|
|
CA
|
A:ASN342
|
3.5
|
19.2
|
1.0
|
|
CB
|
A:ASN342
|
3.5
|
19.2
|
1.0
|
|
C
|
A:ILE345
|
3.6
|
21.3
|
1.0
|
|
C
|
A:ILE377
|
3.6
|
18.9
|
1.0
|
|
HA2
|
A:GLY373
|
3.7
|
18.6
|
1.0
|
|
C
|
A:THR376
|
3.8
|
18.0
|
1.0
|
|
CA
|
A:GLY346
|
3.9
|
21.4
|
1.0
|
|
N
|
A:ILE377
|
3.9
|
18.9
|
1.0
|
|
C
|
A:GLY346
|
4.0
|
21.4
|
1.0
|
|
H
|
A:ILE377
|
4.1
|
18.9
|
1.0
|
|
CA
|
A:THR376
|
4.2
|
18.0
|
1.0
|
|
O
|
A:THR376
|
4.2
|
18.0
|
1.0
|
|
N
|
A:GLY346
|
4.2
|
21.4
|
1.0
|
|
CA
|
A:ILE377
|
4.3
|
18.9
|
1.0
|
|
N
|
A:GLN347
|
4.3
|
22.2
|
1.0
|
|
HA
|
A:ILE377
|
4.3
|
18.9
|
1.0
|
|
HG21
|
A:THR376
|
4.4
|
18.0
|
1.0
|
|
H
|
A:ILE345
|
4.4
|
21.3
|
1.0
|
|
HB2
|
A:ASN342
|
4.4
|
19.2
|
1.0
|
|
HA
|
A:ALA378
|
4.4
|
19.9
|
1.0
|
|
CG2
|
A:THR376
|
4.4
|
18.0
|
1.0
|
|
H
|
A:GLN347
|
4.4
|
22.2
|
1.0
|
|
HA
|
A:GLN347
|
4.5
|
22.2
|
1.0
|
|
O
|
A:GLY346
|
4.5
|
21.4
|
1.0
|
|
O
|
A:GLY373
|
4.5
|
18.6
|
1.0
|
|
HB2
|
A:ALA378
|
4.5
|
19.9
|
1.0
|
|
H
|
A:THR376
|
4.5
|
18.0
|
1.0
|
|
ND2
|
A:ASN342
|
4.5
|
19.2
|
1.0
|
|
HB3
|
A:GLN347
|
4.6
|
22.2
|
1.0
|
|
O
|
A:ALA372
|
4.6
|
18.2
|
1.0
|
|
N
|
A:ILE343
|
4.6
|
19.9
|
1.0
|
|
O
|
A:HOH903
|
4.6
|
16.9
|
1.0
|
|
CA
|
A:GLY373
|
4.6
|
18.6
|
1.0
|
|
N
|
A:ILE345
|
4.7
|
21.3
|
1.0
|
|
N
|
A:ALA378
|
4.7
|
19.9
|
1.0
|
|
HA3
|
A:GLY346
|
4.7
|
21.4
|
1.0
|
|
CA
|
A:ILE345
|
4.8
|
21.3
|
1.0
|
|
N
|
A:THR376
|
4.9
|
18.0
|
1.0
|
|
HD22
|
A:ASN342
|
4.9
|
19.2
|
1.0
|
|
CA
|
A:GLN347
|
4.9
|
22.2
|
1.0
|
|
HG23
|
A:THR376
|
4.9
|
18.0
|
1.0
|
|
N
|
A:ASN342
|
4.9
|
19.2
|
1.0
|
|
HA
|
A:THR376
|
4.9
|
18.0
|
1.0
|
|
CA
|
A:ALA378
|
5.0
|
19.9
|
1.0
|
|
Sodium binding site 2 out
of 6 in 8tz3
Go back to
Sodium Binding Sites List in 8tz3
Sodium binding site 2 out
of 6 in the Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 2 of Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na802
b:19.0
occ:1.00
|
HG
|
A:SER402
|
1.7
|
18.8
|
1.0
|
|
O
|
A:HOH901
|
2.3
|
18.7
|
1.0
|
|
O
|
A:CYS567
|
2.3
|
18.8
|
1.0
|
|
O
|
A:SER375
|
2.4
|
19.0
|
1.0
|
|
OG
|
A:SER402
|
2.4
|
18.8
|
1.0
|
|
SG
|
A:CYS608
|
3.0
|
20.2
|
1.0
|
|
HB3
|
A:SER402
|
3.0
|
18.8
|
1.0
|
|
O
|
A:HOH905
|
3.1
|
17.7
|
1.0
|
|
HB3
|
A:CYS567
|
3.2
|
18.8
|
1.0
|
|
CB
|
A:SER402
|
3.2
|
18.8
|
1.0
|
|
HG
|
A:CYS608
|
3.4
|
20.2
|
1.0
|
|
C
|
A:CYS567
|
3.5
|
18.8
|
1.0
|
|
C
|
A:SER375
|
3.6
|
19.0
|
1.0
|
|
HA
|
A:THR376
|
3.6
|
18.0
|
1.0
|
|
HB2
|
A:SER402
|
3.6
|
18.8
|
1.0
|
|
HA
|
A:CYS608
|
3.8
|
20.2
|
1.0
|
|
CB
|
A:CYS567
|
3.9
|
18.8
|
1.0
|
|
O
|
A:ALA398
|
4.0
|
18.9
|
1.0
|
|
CB
|
A:CYS608
|
4.2
|
20.2
|
1.0
|
|
SG
|
A:CYS567
|
4.3
|
18.8
|
1.0
|
|
HB1
|
A:ALA398
|
4.3
|
18.9
|
1.0
|
|
CA
|
A:CYS567
|
4.3
|
18.8
|
1.0
|
|
HG21
|
A:THR611
|
4.3
|
20.3
|
1.0
|
|
HA
|
A:SER375
|
4.3
|
19.0
|
1.0
|
|
CA
|
A:THR376
|
4.4
|
18.0
|
1.0
|
|
N
|
A:THR376
|
4.4
|
18.0
|
1.0
|
|
HA
|
A:SER399
|
4.4
|
18.6
|
1.0
|
|
HB2
|
A:SER375
|
4.5
|
19.0
|
1.0
|
|
HB3
|
A:CYS608
|
4.5
|
20.2
|
1.0
|
|
HG1
|
A:THR611
|
4.5
|
20.3
|
1.0
|
|
CA
|
A:SER375
|
4.5
|
19.0
|
1.0
|
|
CA
|
A:CYS608
|
4.5
|
20.2
|
1.0
|
|
HA3
|
A:GLY568
|
4.5
|
18.9
|
1.0
|
|
O
|
A:TYR564
|
4.5
|
19.5
|
1.0
|
|
HA
|
A:SER402
|
4.5
|
18.8
|
1.0
|
|
HG22
|
A:THR376
|
4.5
|
18.0
|
1.0
|
|
CA
|
A:SER402
|
4.5
|
18.8
|
1.0
|
|
HA2
|
A:GLY568
|
4.5
|
18.9
|
1.0
|
|
H
|
A:CYS567
|
4.6
|
18.8
|
1.0
|
|
N
|
A:GLY568
|
4.6
|
18.9
|
1.0
|
|
HG
|
A:CYS567
|
4.6
|
18.8
|
1.0
|
|
HB2
|
A:CYS567
|
4.7
|
18.8
|
1.0
|
|
C
|
A:ALA398
|
4.7
|
18.9
|
1.0
|
|
CA
|
A:GLY568
|
4.8
|
18.9
|
1.0
|
|
CB
|
A:SER375
|
4.8
|
19.0
|
1.0
|
|
N
|
A:CYS567
|
4.9
|
18.8
|
1.0
|
|
OG
|
A:SER375
|
4.9
|
19.0
|
1.0
|
|
Sodium binding site 3 out
of 6 in 8tz3
Go back to
Sodium Binding Sites List in 8tz3
Sodium binding site 3 out
of 6 in the Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 3 of Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Na801
b:18.7
occ:1.00
|
O
|
C:HOH901
|
2.4
|
18.4
|
1.0
|
|
OG1
|
C:THR376
|
2.4
|
18.3
|
1.0
|
|
OD1
|
C:ASN342
|
2.4
|
19.5
|
1.0
|
|
O
|
C:ASN342
|
2.5
|
19.5
|
1.0
|
|
O
|
C:ILE377
|
2.5
|
19.3
|
1.0
|
|
O
|
C:ILE345
|
2.5
|
21.6
|
1.0
|
|
HG1
|
C:THR376
|
3.0
|
18.3
|
1.0
|
|
HB
|
C:THR376
|
3.1
|
18.3
|
1.0
|
|
HA
|
C:ASN342
|
3.1
|
19.5
|
1.0
|
|
HB3
|
C:ASN342
|
3.2
|
19.5
|
1.0
|
|
HA2
|
C:GLY346
|
3.2
|
22.1
|
1.0
|
|
CB
|
C:THR376
|
3.3
|
18.3
|
1.0
|
|
CG
|
C:ASN342
|
3.3
|
19.5
|
1.0
|
|
C
|
C:ASN342
|
3.3
|
19.5
|
1.0
|
|
CA
|
C:ASN342
|
3.5
|
19.5
|
1.0
|
|
CB
|
C:ASN342
|
3.5
|
19.5
|
1.0
|
|
C
|
C:ILE345
|
3.6
|
21.6
|
1.0
|
|
C
|
C:ILE377
|
3.6
|
19.3
|
1.0
|
|
HA2
|
C:GLY373
|
3.7
|
18.8
|
1.0
|
|
C
|
C:THR376
|
3.8
|
18.3
|
1.0
|
|
CA
|
C:GLY346
|
3.9
|
22.1
|
1.0
|
|
N
|
C:ILE377
|
3.9
|
19.3
|
1.0
|
|
C
|
C:GLY346
|
4.0
|
22.1
|
1.0
|
|
H
|
C:ILE377
|
4.1
|
19.3
|
1.0
|
|
CA
|
C:THR376
|
4.2
|
18.3
|
1.0
|
|
O
|
C:THR376
|
4.2
|
18.3
|
1.0
|
|
N
|
C:GLY346
|
4.2
|
22.1
|
1.0
|
|
CA
|
C:ILE377
|
4.3
|
19.3
|
1.0
|
|
N
|
C:GLN347
|
4.3
|
22.5
|
1.0
|
|
HA
|
C:ILE377
|
4.3
|
19.3
|
1.0
|
|
HG21
|
C:THR376
|
4.4
|
18.3
|
1.0
|
|
H
|
C:ILE345
|
4.4
|
21.6
|
1.0
|
|
HB2
|
C:ASN342
|
4.4
|
19.5
|
1.0
|
|
HA
|
C:ALA378
|
4.4
|
20.6
|
1.0
|
|
H
|
C:GLN347
|
4.4
|
22.5
|
1.0
|
|
CG2
|
C:THR376
|
4.4
|
18.3
|
1.0
|
|
HA
|
C:GLN347
|
4.5
|
22.5
|
1.0
|
|
O
|
C:GLY346
|
4.5
|
22.1
|
1.0
|
|
O
|
C:GLY373
|
4.5
|
18.8
|
1.0
|
|
HB2
|
C:ALA378
|
4.5
|
20.6
|
1.0
|
|
H
|
C:THR376
|
4.5
|
18.3
|
1.0
|
|
ND2
|
C:ASN342
|
4.5
|
19.5
|
1.0
|
|
HB3
|
C:GLN347
|
4.6
|
22.5
|
1.0
|
|
O
|
C:ALA372
|
4.6
|
18.4
|
1.0
|
|
O
|
C:HOH903
|
4.6
|
17.6
|
1.0
|
|
N
|
C:ILE343
|
4.6
|
20.1
|
1.0
|
|
CA
|
C:GLY373
|
4.6
|
18.8
|
1.0
|
|
N
|
C:ILE345
|
4.7
|
21.6
|
1.0
|
|
N
|
C:ALA378
|
4.7
|
20.6
|
1.0
|
|
HA3
|
C:GLY346
|
4.7
|
22.1
|
1.0
|
|
CA
|
C:ILE345
|
4.8
|
21.6
|
1.0
|
|
N
|
C:THR376
|
4.9
|
18.3
|
1.0
|
|
HD22
|
C:ASN342
|
4.9
|
19.5
|
1.0
|
|
CA
|
C:GLN347
|
4.9
|
22.5
|
1.0
|
|
HG23
|
C:THR376
|
4.9
|
18.3
|
1.0
|
|
N
|
C:ASN342
|
4.9
|
19.5
|
1.0
|
|
HA
|
C:THR376
|
4.9
|
18.3
|
1.0
|
|
CA
|
C:ALA378
|
5.0
|
20.6
|
1.0
|
|
Sodium binding site 4 out
of 6 in 8tz3
Go back to
Sodium Binding Sites List in 8tz3
Sodium binding site 4 out
of 6 in the Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 4 of Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Na802
b:18.7
occ:1.00
|
HG
|
C:SER402
|
1.6
|
19.1
|
1.0
|
|
O
|
C:HOH902
|
2.3
|
18.2
|
1.0
|
|
O
|
C:CYS567
|
2.3
|
18.9
|
1.0
|
|
O
|
C:SER375
|
2.4
|
19.0
|
1.0
|
|
OG
|
C:SER402
|
2.4
|
19.1
|
1.0
|
|
SG
|
C:CYS608
|
3.0
|
20.1
|
1.0
|
|
O
|
C:HOH905
|
3.0
|
17.8
|
1.0
|
|
HB3
|
C:SER402
|
3.0
|
19.1
|
1.0
|
|
HB3
|
C:CYS567
|
3.2
|
18.9
|
1.0
|
|
CB
|
C:SER402
|
3.2
|
19.1
|
1.0
|
|
C
|
C:CYS567
|
3.5
|
18.9
|
1.0
|
|
C
|
C:SER375
|
3.6
|
19.0
|
1.0
|
|
HG
|
C:CYS608
|
3.6
|
20.1
|
1.0
|
|
HA
|
C:THR376
|
3.6
|
18.3
|
1.0
|
|
HB2
|
C:SER402
|
3.6
|
19.1
|
1.0
|
|
HA
|
C:CYS608
|
3.8
|
20.1
|
1.0
|
|
CB
|
C:CYS567
|
3.9
|
18.9
|
1.0
|
|
O
|
C:ALA398
|
4.0
|
19.1
|
1.0
|
|
HB1
|
C:ALA398
|
4.2
|
19.1
|
1.0
|
|
CB
|
C:CYS608
|
4.2
|
20.1
|
1.0
|
|
SG
|
C:CYS567
|
4.3
|
18.9
|
1.0
|
|
CA
|
C:CYS567
|
4.3
|
18.9
|
1.0
|
|
HG21
|
C:THR611
|
4.3
|
20.2
|
1.0
|
|
HA
|
C:SER375
|
4.3
|
19.0
|
1.0
|
|
HG1
|
C:THR611
|
4.4
|
20.2
|
1.0
|
|
CA
|
C:THR376
|
4.4
|
18.3
|
1.0
|
|
HA
|
C:SER399
|
4.4
|
18.9
|
1.0
|
|
N
|
C:THR376
|
4.4
|
18.3
|
1.0
|
|
HB2
|
C:SER375
|
4.5
|
19.0
|
1.0
|
|
HB3
|
C:CYS608
|
4.5
|
20.1
|
1.0
|
|
CA
|
C:SER375
|
4.5
|
19.0
|
1.0
|
|
CA
|
C:CYS608
|
4.5
|
20.1
|
1.0
|
|
HA
|
C:SER402
|
4.5
|
19.1
|
1.0
|
|
HA3
|
C:GLY568
|
4.5
|
19.1
|
1.0
|
|
O
|
C:TYR564
|
4.5
|
19.4
|
1.0
|
|
HG22
|
C:THR376
|
4.5
|
18.3
|
1.0
|
|
CA
|
C:SER402
|
4.5
|
19.1
|
1.0
|
|
HA2
|
C:GLY568
|
4.5
|
19.1
|
1.0
|
|
HG
|
C:CYS567
|
4.5
|
18.9
|
1.0
|
|
H
|
C:CYS567
|
4.6
|
18.9
|
1.0
|
|
N
|
C:GLY568
|
4.6
|
19.1
|
1.0
|
|
HB2
|
C:CYS567
|
4.7
|
18.9
|
1.0
|
|
C
|
C:ALA398
|
4.7
|
19.1
|
1.0
|
|
CA
|
C:GLY568
|
4.8
|
19.1
|
1.0
|
|
CB
|
C:SER375
|
4.8
|
19.0
|
1.0
|
|
N
|
C:CYS567
|
4.9
|
18.9
|
1.0
|
|
OG
|
C:SER375
|
4.9
|
19.0
|
1.0
|
|
Sodium binding site 5 out
of 6 in 8tz3
Go back to
Sodium Binding Sites List in 8tz3
Sodium binding site 5 out
of 6 in the Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 5 of Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Na801
b:18.1
occ:1.00
|
OG1
|
B:THR376
|
2.4
|
18.3
|
1.0
|
|
O
|
B:HOH901
|
2.4
|
18.9
|
1.0
|
|
OD1
|
B:ASN342
|
2.4
|
19.8
|
1.0
|
|
O
|
B:ASN342
|
2.5
|
19.8
|
1.0
|
|
O
|
B:ILE377
|
2.5
|
19.2
|
1.0
|
|
O
|
B:ILE345
|
2.5
|
21.9
|
1.0
|
|
HB
|
B:THR376
|
3.1
|
18.3
|
1.0
|
|
HG1
|
B:THR376
|
3.1
|
18.3
|
1.0
|
|
HA
|
B:ASN342
|
3.1
|
19.8
|
1.0
|
|
HB3
|
B:ASN342
|
3.2
|
19.8
|
1.0
|
|
HA2
|
B:GLY346
|
3.2
|
22.0
|
1.0
|
|
CB
|
B:THR376
|
3.3
|
18.3
|
1.0
|
|
CG
|
B:ASN342
|
3.3
|
19.8
|
1.0
|
|
C
|
B:ASN342
|
3.3
|
19.8
|
1.0
|
|
CA
|
B:ASN342
|
3.5
|
19.8
|
1.0
|
|
CB
|
B:ASN342
|
3.5
|
19.8
|
1.0
|
|
C
|
B:ILE345
|
3.6
|
21.9
|
1.0
|
|
C
|
B:ILE377
|
3.6
|
19.2
|
1.0
|
|
HA2
|
B:GLY373
|
3.7
|
19.1
|
1.0
|
|
C
|
B:THR376
|
3.8
|
18.3
|
1.0
|
|
CA
|
B:GLY346
|
3.9
|
22.0
|
1.0
|
|
N
|
B:ILE377
|
3.9
|
19.2
|
1.0
|
|
C
|
B:GLY346
|
4.0
|
22.0
|
1.0
|
|
H
|
B:ILE377
|
4.1
|
19.2
|
1.0
|
|
CA
|
B:THR376
|
4.2
|
18.3
|
1.0
|
|
O
|
B:THR376
|
4.2
|
18.3
|
1.0
|
|
N
|
B:GLY346
|
4.2
|
22.0
|
1.0
|
|
CA
|
B:ILE377
|
4.3
|
19.2
|
1.0
|
|
N
|
B:GLN347
|
4.3
|
22.8
|
1.0
|
|
HA
|
B:ILE377
|
4.3
|
19.2
|
1.0
|
|
HG21
|
B:THR376
|
4.3
|
18.3
|
1.0
|
|
H
|
B:ILE345
|
4.4
|
21.9
|
1.0
|
|
HB2
|
B:ASN342
|
4.4
|
19.8
|
1.0
|
|
HA
|
B:ALA378
|
4.4
|
20.2
|
1.0
|
|
H
|
B:GLN347
|
4.4
|
22.8
|
1.0
|
|
CG2
|
B:THR376
|
4.4
|
18.3
|
1.0
|
|
HA
|
B:GLN347
|
4.5
|
22.8
|
1.0
|
|
O
|
B:GLY346
|
4.5
|
22.0
|
1.0
|
|
O
|
B:GLY373
|
4.5
|
19.1
|
1.0
|
|
HB2
|
B:ALA378
|
4.5
|
20.2
|
1.0
|
|
H
|
B:THR376
|
4.5
|
18.3
|
1.0
|
|
ND2
|
B:ASN342
|
4.5
|
19.8
|
1.0
|
|
HB3
|
B:GLN347
|
4.6
|
22.8
|
1.0
|
|
O
|
B:ALA372
|
4.6
|
18.7
|
1.0
|
|
N
|
B:ILE343
|
4.6
|
20.1
|
1.0
|
|
CA
|
B:GLY373
|
4.6
|
19.1
|
1.0
|
|
O
|
B:HOH903
|
4.6
|
17.4
|
1.0
|
|
N
|
B:ILE345
|
4.7
|
21.9
|
1.0
|
|
N
|
B:ALA378
|
4.7
|
20.2
|
1.0
|
|
HA3
|
B:GLY346
|
4.7
|
22.0
|
1.0
|
|
CA
|
B:ILE345
|
4.8
|
21.9
|
1.0
|
|
N
|
B:THR376
|
4.9
|
18.3
|
1.0
|
|
HD22
|
B:ASN342
|
4.9
|
19.8
|
1.0
|
|
CA
|
B:GLN347
|
4.9
|
22.8
|
1.0
|
|
N
|
B:ASN342
|
4.9
|
19.8
|
1.0
|
|
HG23
|
B:THR376
|
4.9
|
18.3
|
1.0
|
|
HA
|
B:THR376
|
4.9
|
18.3
|
1.0
|
|
CA
|
B:ALA378
|
5.0
|
20.2
|
1.0
|
|
Sodium binding site 6 out
of 6 in 8tz3
Go back to
Sodium Binding Sites List in 8tz3
Sodium binding site 6 out
of 6 in the Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 6 of Cryo-Em Structure of Bovine Concentrative Nucleoside Transporter 3 in Complex with Gs-441524, Consensus Reconstruction within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Na802
b:18.6
occ:1.00
|
HG
|
B:SER402
|
1.7
|
18.9
|
1.0
|
|
O
|
B:HOH902
|
2.3
|
18.0
|
1.0
|
|
O
|
B:CYS567
|
2.3
|
19.0
|
1.0
|
|
O
|
B:SER375
|
2.4
|
19.2
|
1.0
|
|
OG
|
B:SER402
|
2.4
|
18.9
|
1.0
|
|
O
|
B:HOH905
|
3.0
|
18.1
|
1.0
|
|
SG
|
B:CYS608
|
3.0
|
20.2
|
1.0
|
|
HB3
|
B:SER402
|
3.0
|
18.9
|
1.0
|
|
HB3
|
B:CYS567
|
3.2
|
19.0
|
1.0
|
|
CB
|
B:SER402
|
3.2
|
18.9
|
1.0
|
|
C
|
B:CYS567
|
3.5
|
19.0
|
1.0
|
|
C
|
B:SER375
|
3.6
|
19.2
|
1.0
|
|
HG
|
B:CYS608
|
3.6
|
20.2
|
1.0
|
|
HA
|
B:THR376
|
3.6
|
18.3
|
1.0
|
|
HB2
|
B:SER402
|
3.6
|
18.9
|
1.0
|
|
HA
|
B:CYS608
|
3.8
|
20.2
|
1.0
|
|
CB
|
B:CYS567
|
3.9
|
19.0
|
1.0
|
|
O
|
B:ALA398
|
4.0
|
18.6
|
1.0
|
|
HB1
|
B:ALA398
|
4.2
|
18.6
|
1.0
|
|
CB
|
B:CYS608
|
4.2
|
20.2
|
1.0
|
|
SG
|
B:CYS567
|
4.3
|
19.0
|
1.0
|
|
CA
|
B:CYS567
|
4.3
|
19.0
|
1.0
|
|
HG21
|
B:THR611
|
4.3
|
20.2
|
1.0
|
|
HA
|
B:SER375
|
4.3
|
19.2
|
1.0
|
|
HG1
|
B:THR611
|
4.4
|
20.2
|
1.0
|
|
HA
|
B:SER399
|
4.4
|
18.8
|
1.0
|
|
N
|
B:THR376
|
4.4
|
18.3
|
1.0
|
|
CA
|
B:THR376
|
4.4
|
18.3
|
1.0
|
|
HB2
|
B:SER375
|
4.5
|
19.2
|
1.0
|
|
HB3
|
B:CYS608
|
4.5
|
20.2
|
1.0
|
|
CA
|
B:SER375
|
4.5
|
19.2
|
1.0
|
|
CA
|
B:CYS608
|
4.5
|
20.2
|
1.0
|
|
O
|
B:TYR564
|
4.5
|
19.2
|
1.0
|
|
HA3
|
B:GLY568
|
4.5
|
19.1
|
1.0
|
|
HA
|
B:SER402
|
4.5
|
18.9
|
1.0
|
|
CA
|
B:SER402
|
4.5
|
18.9
|
1.0
|
|
HA2
|
B:GLY568
|
4.5
|
19.1
|
1.0
|
|
HG22
|
B:THR376
|
4.5
|
18.3
|
1.0
|
|
HG
|
B:CYS567
|
4.6
|
19.0
|
1.0
|
|
H
|
B:CYS567
|
4.6
|
19.0
|
1.0
|
|
N
|
B:GLY568
|
4.6
|
19.1
|
1.0
|
|
HB2
|
B:CYS567
|
4.7
|
19.0
|
1.0
|
|
C
|
B:ALA398
|
4.7
|
18.6
|
1.0
|
|
CA
|
B:GLY568
|
4.8
|
19.1
|
1.0
|
|
CB
|
B:SER375
|
4.8
|
19.2
|
1.0
|
|
N
|
B:CYS567
|
4.9
|
19.0
|
1.0
|
|
OG
|
B:SER375
|
4.9
|
19.2
|
1.0
|
|
Reference:
N.J.Wright,
F.Zhang,
Y.Suo,
L.Kong,
Y.Yin,
J.G.Fedor,
K.Sharma,
M.J.Borgnia,
W.Im,
S.Y.Lee.
Antiviral Drug Recognition and Elevator-Type Transport Motions of CNT3. Nat.Chem.Biol. 2024.
ISSN: ESSN 1552-4469
PubMed: 38418906
DOI: 10.1038/S41589-024-01559-8
Page generated: Wed Oct 9 13:45:31 2024
|
