Sodium in PDB 8twr: Influenza A Virus (A/Aichi/2/1968(H3N2) Nucleoprotein Mutant - 2-7 Deleted, P283S, R416A

The structure of Influenza A Virus (A/Aichi/2/1968(H3N2) Nucleoprotein Mutant - 2-7 Deleted, P283S, R416A, PDB code: 8twr was solved by J.Yoon, Y.M.Zhang, R.A.Grant, M.D.Shoulders, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.92 / 3.09
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	163.42, 285.22, 116.9, 90, 90, 90
R / Rfree (%)	21.9 / 23.5

The binding sites of Sodium atom in the Influenza A Virus (A/Aichi/2/1968(H3N2) Nucleoprotein Mutant - 2-7 Deleted, P283S, R416A (pdb code 8twr). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Influenza A Virus (A/Aichi/2/1968(H3N2) Nucleoprotein Mutant - 2-7 Deleted, P283S, R416A, PDB code: 8twr:

Sodium binding site 1 out of 1 in the Influenza A Virus (A/Aichi/2/1968(H3N2) Nucleoprotein Mutant - 2-7 Deleted, P283S, R416A


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Influenza A Virus (A/Aichi/2/1968(H3N2) Nucleoprotein Mutant - 2-7 Deleted, P283S, R416A within 5.0Å range: probe atom residue distance (Å) B Occ B:Na601 b:73.2 occ:1.00 OD1 B:ASN492 2.7 100.4 1.0 O B:ARG355 2.8 86.4 1.0 O B:LEU358 3.0 85.4 1.0 O A:MET481 3.1 96.7 1.0 O B:GLY356 3.6 91.5 1.0 CG B:ASN492 3.7 99.3 1.0 C B:GLY356 3.9 88.5 1.0 C A:MET481 3.9 91.9 1.0 C B:ARG355 3.9 83.9 1.0 CA B:GLY356 3.9 86.9 1.0 CB A:MET481 3.9 87.7 1.0 ND2 B:ASN492 4.0 101.5 1.0 C B:LEU358 4.0 86.8 1.0 N B:LEU358 4.1 82.3 1.0 O B:THR360 4.3 78.2 1.0 N B:GLY356 4.4 87.8 1.0 CB B:LEU358 4.4 81.7 1.0 CA B:LEU358 4.4 82.6 1.0 CA A:MET481 4.5 87.5 1.0 N A:SER482 4.6 87.6 1.0 N B:LYS357 4.7 86.0 1.0 C B:ASN492 4.8 90.5 1.0 CG B:ARG355 4.8 80.6 1.0 CA A:SER482 4.8 83.6 1.0 O B:ASN492 4.8 95.0 1.0 N B:ALA493 4.8 90.1 1.0 CA B:ALA493 5.0 87.9 1.0 CB B:ASN492 5.0 91.1 1.0

J.Yoon, Y.M.Zhang, C.Her, R.A.Grant, A.M.Ponomarenko, B.E.Ackermann, G.T.Debelouchina, M.D.Shoulders. The Immune-Evasive Proline-283 Substitution in Influenza Nucleoprotein Increases Aggregation Propensity Without Altering the Native Structure Sci Adv 2024.
ISSN: ESSN 2375-2548