Sodium in PDB 8trt: Structure of the EPHA2 Crd Bound to FABS1CE_C1, Monoclinic Form

All present enzymatic activity of Structure of the EPHA2 Crd Bound to FABS1CE_C1, Monoclinic Form:
2.7.10.1;

The structure of Structure of the EPHA2 Crd Bound to FABS1CE_C1, Monoclinic Form, PDB code: 8trt was solved by A.U.Singer, H.A.Bruce, L.Blazer, J.J.Adams, F.Sicheri, S.S.Sidhu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	68.78 / 3.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	57.71, 182.135, 74.38, 90, 92.93, 90
R / Rfree (%)	19.4 / 24.4

The structure of Structure of the EPHA2 Crd Bound to FABS1CE_C1, Monoclinic Form also contains other interesting chemical elements:

Chlorine

(Cl)

4 atoms

The binding sites of Sodium atom in the Structure of the EPHA2 Crd Bound to FABS1CE_C1, Monoclinic Form (pdb code 8trt). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Structure of the EPHA2 Crd Bound to FABS1CE_C1, Monoclinic Form, PDB code: 8trt:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Structure of the EPHA2 Crd Bound to FABS1CE_C1, Monoclinic Form


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structure of the EPHA2 Crd Bound to FABS1CE_C1, Monoclinic Form within 5.0Å range: probe atom residue distance (Å) B Occ B:Na302 b:40.8 occ:1.00 OD2 B:ASP232 3.2 48.5 1.0 ND2 B:ASN221 3.2 40.8 1.0 CE B:LYS230 3.3 47.1 1.0 CG B:ASN221 3.5 41.7 1.0 OG B:SER180 3.5 37.9 1.0 NZ B:LYS230 3.6 49.0 1.0 OD1 B:ASP232 3.6 46.1 1.0 CB B:ASN221 3.7 40.3 1.0 CG B:ASP232 3.8 46.3 1.0 CD B:LYS230 3.9 48.6 1.0 OD1 B:ASN221 4.2 43.6 1.0 CB B:SER180 4.6 39.4 1.0 CA B:SER180 4.6 38.9 1.0 CG B:LYS230 4.9 45.9 1.0 CA B:ASN221 5.0 36.5 1.0

Sodium binding site 2 out of 2 in the Structure of the EPHA2 Crd Bound to FABS1CE_C1, Monoclinic Form


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Structure of the EPHA2 Crd Bound to FABS1CE_C1, Monoclinic Form within 5.0Å range: probe atom residue distance (Å) B Occ B:Na303 b:40.4 occ:1.00 ND1 B:HIS188 3.1 35.3 1.0 CE1 B:HIS188 3.6 36.0 1.0 CB C:THR182 4.2 34.3 1.0 CG B:HIS188 4.3 34.0 1.0 O B:VAL187 4.3 30.9 1.0 OG1 C:THR182 4.3 34.1 1.0 OD1 C:ASP185 4.4 43.6 1.0 CG2 C:THR182 4.5 33.5 1.0 O C:GLU183 4.6 42.4 1.0 CA B:HIS188 4.7 33.0 1.0 CB B:HIS188 4.8 33.1 1.0 NE2 B:HIS188 4.8 35.9 1.0

H.A.Bruce, A.U.Singer, E.V.Filippova, L.L.Blazer, J.J.Adams, L.Enderle, M.Ben-David, E.H.Radley, D.Y.L.Mao, V.Pau, S.Orlicky, F.Sicheri, I.Kourinov, S.Atwell, A.A.Kossiakoff, S.S.Sidhu. Engineered Antigen-Binding Fragments For Enhanced Crystallization of Antibody:Antigen Complexes. Protein Sci. E4824 2023.
ISSN: ESSN 1469-896X
PubMed: 37945533
DOI: 10.1002/PRO.4824