Sodium in PDB 8pxv: Targeting Extended Blood Antigens By Akkermansia Muciniphila Enzymes Unveils A Missing Link For Generating Universal Donor Blood

The structure of Targeting Extended Blood Antigens By Akkermansia Muciniphila Enzymes Unveils A Missing Link For Generating Universal Donor Blood, PDB code: 8pxv was solved by J.Weikum, M.Jensen, M.Abou Hachem, J.P.Morth, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	54.32 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	96.26, 170.42, 171.94, 90, 90, 90
R / Rfree (%)	17.8 / 21.2

The binding sites of Sodium atom in the Targeting Extended Blood Antigens By Akkermansia Muciniphila Enzymes Unveils A Missing Link For Generating Universal Donor Blood (pdb code 8pxv). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Targeting Extended Blood Antigens By Akkermansia Muciniphila Enzymes Unveils A Missing Link For Generating Universal Donor Blood, PDB code: 8pxv:

Sodium binding site 1 out of 1 in the Targeting Extended Blood Antigens By Akkermansia Muciniphila Enzymes Unveils A Missing Link For Generating Universal Donor Blood


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Targeting Extended Blood Antigens By Akkermansia Muciniphila Enzymes Unveils A Missing Link For Generating Universal Donor Blood within 5.0Å range: probe atom residue distance (Å) B Occ C:Na701 b:56.0 occ:1.00 HG C:SER212 2.4 53.9 1.0 OD2 C:ASP223 2.4 46.9 1.0 OG C:SER212 2.7 44.9 1.0 HB2 C:SER212 2.8 58.1 1.0 O C:THR225 2.8 48.5 1.0 HB2 C:HIS227 2.9 49.5 1.0 HB C:THR225 3.2 64.7 1.0 CG C:ASP223 3.2 50.1 1.0 CB C:SER212 3.2 48.4 1.0 OD1 C:ASP223 3.3 50.4 1.0 O C:HOH834 3.5 44.3 1.0 H C:SER212 3.5 56.4 1.0 N C:SER212 3.7 47.0 1.0 HA C:GLU211 3.8 59.0 1.0 CB C:HIS227 3.9 41.3 1.0 C C:THR225 3.9 49.9 1.0 HG22 C:THR225 4.0 63.4 1.0 HB3 C:SER212 4.0 58.1 1.0 CB C:THR225 4.0 53.9 1.0 H C:THR225 4.1 61.8 1.0 CA C:SER212 4.1 49.6 1.0 HB3 C:HIS227 4.1 49.5 1.0 HH21 C:ARG209 4.2 54.7 1.0 C C:GLU211 4.2 47.3 1.0 O C:HOH845 4.2 42.3 1.0 CA C:THR225 4.4 50.5 1.0 HE C:ARG209 4.4 45.0 1.0 CA C:GLU211 4.5 49.2 1.0 HE22 B:GLN620 4.5 64.8 1.0 CG2 C:THR225 4.5 52.9 1.0 CG C:HIS227 4.6 43.0 1.0 O C:PRO226 4.6 48.5 1.0 C C:PRO226 4.6 46.3 1.0 HD1 C:HIS227 4.7 53.7 1.0 N C:THR225 4.7 51.5 1.0 CB C:ASP223 4.7 48.4 1.0 N C:HIS227 4.7 42.4 1.0 HA C:SER212 4.8 59.5 1.0 NE2 C:HIS160 4.8 41.0 1.0 HD2 C:HIS160 4.8 48.8 1.0 HG21 C:THR225 4.8 63.4 1.0 CA C:HIS227 4.8 42.3 1.0 NH2 C:ARG209 4.8 45.6 1.0 ND1 C:HIS227 4.9 44.7 1.0 O C:GLU211 4.9 47.2 1.0 HB2 C:ASP223 4.9 58.1 1.0 HB3 C:ASP223 5.0 58.1 1.0 HA C:HIS227 5.0 50.8 1.0 O C:SER212 5.0 49.2 1.0

M.Jensen, L.Stenfelt, J.R.Hagman, M.J.Pichler, J.Weikum, T.S.Nielsen, A.Hult, J.P.Morth, M.L.Olsson, M.Abou Hachem. Akkermansia Muciniphila Exoglycosidases Target Extended Blood Group Antigens to Generate Abo-Universal Blood Nature Microbiology 2024.