Atomistry » Sodium » PDB 8oyg-8pha » 8pe9
Atomistry »
  Sodium »
    PDB 8oyg-8pha »
      8pe9 »

Sodium in PDB 8pe9: Complex Between DDR1 Ds-Like Domain and Prth-101 Fab

Enzymatic activity of Complex Between DDR1 Ds-Like Domain and Prth-101 Fab

All present enzymatic activity of Complex Between DDR1 Ds-Like Domain and Prth-101 Fab:
2.7.10.1;

Protein crystallography data

The structure of Complex Between DDR1 Ds-Like Domain and Prth-101 Fab, PDB code: 8pe9 was solved by J.Liu, H.Chiang, W.Xiong, V.Laurent, S.C.Griffiths, J.Duelfer, H.Deng, X.Sun, Y.W.Yin, W.Li, L.P.Audoly, Z.An, T.Schuerpf, R.Li, N.Zhang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 72.22 / 3.15
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 117.096, 144.45, 52.299, 90, 90, 90
R / Rfree (%) 27.8 / 30.9

Other elements in 8pe9:

The structure of Complex Between DDR1 Ds-Like Domain and Prth-101 Fab also contains other interesting chemical elements:

Calcium (Ca) 1 atom
Zinc (Zn) 3 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the Complex Between DDR1 Ds-Like Domain and Prth-101 Fab (pdb code 8pe9). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Complex Between DDR1 Ds-Like Domain and Prth-101 Fab, PDB code: 8pe9:

Sodium binding site 1 out of 1 in 8pe9

Go back to Sodium Binding Sites List in 8pe9
Sodium binding site 1 out of 1 in the Complex Between DDR1 Ds-Like Domain and Prth-101 Fab


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Complex Between DDR1 Ds-Like Domain and Prth-101 Fab within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na5004

b:22.5
occ:1.00
CE1 A:PHE263 2.8 68.2 1.0
CD1 A:PHE263 3.1 67.5 1.0
O A:TYR267 3.5 62.8 1.0
N A:GLU269 3.8 62.1 1.0
CZ A:PHE263 4.0 68.0 1.0
OG A:SER265 4.2 67.7 1.0
CG A:PRO197 4.2 67.0 1.0
CB A:GLU269 4.4 64.3 1.0
CA A:VAL268 4.4 62.4 1.0
CG A:PHE263 4.5 66.6 1.0
C A:TYR267 4.6 62.7 1.0
C A:VAL268 4.6 62.4 1.0
CA A:GLU269 4.7 62.2 1.0
OH H:TYR55 5.0 57.0 1.0
N A:VAL268 5.0 62.2 1.0

Reference:

J.Liu, H.C.Chiang, W.Xiong, V.Laurent, S.C.Griffiths, J.Dulfer, H.Deng, X.Sun, Y.W.Yin, W.Li, L.P.Audoly, Z.An, T.Schurpf, R.Li, N.Zhang. A Highly Selective Humanized DDR1 Mab Reverses Immune Exclusion By Disrupting Collagen Fiber Alignment in Breast Cancer. J Immunother Cancer V. 11 2023.
ISSN: ESSN 2051-1426
PubMed: 37328286
DOI: 10.1136/JITC-2023-006720
Page generated: Wed Oct 9 12:55:16 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy