Sodium in PDB 8itz: Crystal Structure of Human Galectin-3 in Complex with Small Molecule Inhibitor

The structure of Crystal Structure of Human Galectin-3 in Complex with Small Molecule Inhibitor, PDB code: 8itz was solved by S.Jinal, K.Amit, K.Ghosh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.82 / 1.22
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.51, 57.241, 61.257, 90, 90, 90
R / Rfree (%)	14.7 / 17.3

The structure of Crystal Structure of Human Galectin-3 in Complex with Small Molecule Inhibitor also contains other interesting chemical elements:

Fluorine	(F)	3 atoms
Chlorine	(Cl)	3 atoms

The binding sites of Sodium atom in the Crystal Structure of Human Galectin-3 in Complex with Small Molecule Inhibitor (pdb code 8itz). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Human Galectin-3 in Complex with Small Molecule Inhibitor, PDB code: 8itz:

Sodium binding site 1 out of 1 in the Crystal Structure of Human Galectin-3 in Complex with Small Molecule Inhibitor


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Human Galectin-3 in Complex with Small Molecule Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Na303 b:21.9 occ:1.00 O A:HOH532 2.9 37.6 1.0 HG2 A:GLU230 4.3 9.7 1.0 O A:HOH444 4.5 23.8 1.0 OE2 A:GLU230 4.9 15.8 1.0

J.J.Swidorski, B.B.Beno, C.Liu, D.Yoon, K.Ghosh, H.Sale, D.Shah, K.Acharya, J.Yanchunas, B.Ellsworth, D.Cheng, A.Regueiro-Ren. Discovery and Exploration of Monosaccharide Linked Dimers to Target Fibrosis To Be Published.