Sodium in PDB 8hir: Potassium Channels

The structure of Potassium Channels also contains other interesting chemical elements:

Potassium	(K)	4 atoms
Zinc	(Zn)	4 atoms

The binding sites of Sodium atom in the Potassium Channels (pdb code 8hir). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 4 binding sites of Sodium where determined in the Potassium Channels, PDB code: 8hir:
Jump to Sodium binding site number: 1; 2; 3; 4;

Sodium binding site 1 out of 4 in the Potassium Channels


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Potassium Channels within 5.0Å range: probe atom residue distance (Å) B Occ A:Na1301 b:59.9 occ:1.00 OE1 A:GLU560 2.3 71.8 1.0 O A:LEU532 2.3 61.0 1.0 O A:HIS535 2.5 65.3 1.0 OE2 A:GLU560 2.7 84.9 1.0 O A:SER557 2.8 61.5 1.0 CD A:GLU560 2.9 79.9 1.0 O A:ASN559 3.5 78.9 1.0 C A:LEU532 3.5 55.8 1.0 OG A:SER537 3.6 82.4 1.0 C A:HIS535 3.7 62.5 1.0 C A:SER557 3.9 63.2 1.0 C A:GLY558 3.9 80.4 1.0 CA A:GLY558 4.0 76.6 1.0 N A:ASN559 4.0 71.1 1.0 C A:ASN559 4.1 68.2 1.0 N A:SER537 4.3 77.7 1.0 CA A:LEU532 4.4 54.2 1.0 CG A:GLU560 4.4 77.9 1.0 N A:GLY558 4.4 73.0 1.0 O A:GLY558 4.4 80.7 1.0 N A:LEU533 4.5 42.4 1.0 N A:HIS535 4.5 57.8 1.0 CA A:HIS535 4.5 58.8 1.0 CA A:LEU533 4.6 38.1 1.0 CB A:SER537 4.6 81.4 1.0 CB A:LEU532 4.6 43.7 1.0 C A:LEU533 4.7 52.5 1.0 N A:THR536 4.7 73.6 1.0 O A:LEU533 4.7 63.3 1.0 CB A:HIS535 4.7 53.6 1.0 CA A:THR536 4.7 70.2 1.0 CA A:ASN559 4.8 66.8 1.0 N A:GLU560 4.9 69.2 1.0 CD1 A:LEU956 4.9 91.8 1.0 C A:THR536 4.9 78.7 1.0 O A:SER537 5.0 82.2 1.0 CA A:SER537 5.0 78.7 1.0

Sodium binding site 2 out of 4 in the Potassium Channels


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Potassium Channels within 5.0Å range: probe atom residue distance (Å) B Occ B:Na1302 b:58.8 occ:1.00 O B:LEU532 2.3 61.6 1.0 OE1 B:GLU560 2.3 72.6 1.0 O B:HIS535 2.5 66.2 1.0 OE2 B:GLU560 2.7 85.5 1.0 O B:SER557 2.8 63.1 1.0 CD B:GLU560 2.9 80.4 1.0 O B:ASN559 3.5 77.7 1.0 C B:LEU532 3.5 56.1 1.0 OG B:SER537 3.6 83.6 1.0 C B:HIS535 3.7 63.5 1.0 C B:SER557 3.9 64.5 1.0 C B:GLY558 3.9 80.2 1.0 CA B:GLY558 4.0 76.3 1.0 N B:ASN559 4.0 70.9 1.0 C B:ASN559 4.1 67.1 1.0 N B:SER537 4.3 78.1 1.0 CA B:LEU532 4.4 54.0 1.0 CG B:GLU560 4.4 78.4 1.0 N B:GLY558 4.4 73.3 1.0 O B:GLY558 4.4 80.9 1.0 N B:LEU533 4.5 43.6 1.0 N B:HIS535 4.5 58.0 1.0 CA B:HIS535 4.5 59.5 1.0 CA B:LEU533 4.6 40.1 1.0 CB B:SER537 4.6 82.5 1.0 CB B:LEU532 4.6 44.4 1.0 N B:THR536 4.7 75.8 1.0 C B:LEU533 4.7 53.0 1.0 O B:LEU533 4.7 63.3 1.0 CB B:HIS535 4.7 55.1 1.0 CA B:THR536 4.7 72.3 1.0 CA B:ASN559 4.8 66.5 1.0 CD1 B:LEU956 4.9 91.6 1.0 N B:GLU560 4.9 69.0 1.0 C B:THR536 4.9 79.8 1.0 CA B:SER537 5.0 79.1 1.0 O B:SER537 5.0 84.5 1.0

Sodium binding site 3 out of 4 in the Potassium Channels


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Potassium Channels within 5.0Å range: probe atom residue distance (Å) B Occ C:Na1302 b:57.3 occ:1.00 O C:LEU532 2.3 60.9 1.0 OE1 C:GLU560 2.3 72.3 1.0 O C:HIS535 2.5 65.6 1.0 OE2 C:GLU560 2.7 85.9 1.0 CD C:GLU560 2.8 80.2 1.0 O C:SER557 2.8 61.5 1.0 O C:ASN559 3.5 78.6 1.0 C C:LEU532 3.5 55.5 1.0 OG C:SER537 3.6 83.2 1.0 C C:HIS535 3.7 63.8 1.0 C C:SER557 3.9 64.0 1.0 C C:GLY558 4.0 80.4 1.0 CA C:GLY558 4.0 76.6 1.0 N C:ASN559 4.1 71.1 1.0 C C:ASN559 4.1 67.7 1.0 N C:SER537 4.3 78.2 1.0 CG C:GLU560 4.3 78.3 1.0 CA C:LEU532 4.4 54.3 1.0 N C:GLY558 4.4 73.6 1.0 O C:GLY558 4.4 80.3 1.0 N C:LEU533 4.5 42.6 1.0 N C:HIS535 4.5 58.2 1.0 CA C:HIS535 4.5 60.3 1.0 CA C:LEU533 4.5 37.9 1.0 CB C:SER537 4.6 82.1 1.0 C C:LEU533 4.6 53.1 1.0 N C:THR536 4.6 75.2 1.0 CB C:LEU532 4.7 44.0 1.0 O C:LEU533 4.7 63.5 1.0 CA C:THR536 4.7 71.5 1.0 CB C:HIS535 4.7 55.4 1.0 CA C:ASN559 4.8 66.8 1.0 C C:THR536 4.9 79.9 1.0 CD1 C:LEU956 4.9 91.3 1.0 N C:GLU560 4.9 69.4 1.0 O C:SER537 5.0 84.4 1.0 CA C:SER537 5.0 79.1 1.0

Sodium binding site 4 out of 4 in the Potassium Channels


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 4 of Potassium Channels within 5.0Å range: probe atom residue distance (Å) B Occ D:Na1302 b:59.2 occ:1.00 OE1 D:GLU560 2.3 71.5 1.0 O D:LEU532 2.3 61.7 1.0 O D:HIS535 2.5 65.0 1.0 OE2 D:GLU560 2.7 85.5 1.0 O D:SER557 2.8 61.2 1.0 CD D:GLU560 2.9 80.1 1.0 O D:ASN559 3.5 79.1 1.0 C D:LEU532 3.5 56.1 1.0 OG D:SER537 3.7 84.0 1.0 C D:HIS535 3.7 62.4 1.0 C D:SER557 3.9 63.4 1.0 C D:GLY558 3.9 80.1 1.0 CA D:GLY558 4.0 76.5 1.0 N D:ASN559 4.0 71.1 1.0 C D:ASN559 4.1 67.3 1.0 N D:SER537 4.3 77.7 1.0 CA D:LEU532 4.4 53.6 1.0 CG D:GLU560 4.4 78.0 1.0 N D:GLY558 4.4 73.5 1.0 O D:GLY558 4.4 80.8 1.0 N D:LEU533 4.5 43.0 1.0 N D:HIS535 4.5 58.3 1.0 CA D:HIS535 4.5 58.7 1.0 CA D:LEU533 4.6 38.6 1.0 CB D:SER537 4.6 82.9 1.0 CB D:LEU532 4.6 43.6 1.0 C D:LEU533 4.7 53.1 1.0 N D:THR536 4.7 74.1 1.0 O D:LEU533 4.7 63.0 1.0 CB D:HIS535 4.7 54.1 1.0 CA D:THR536 4.7 71.3 1.0 CA D:ASN559 4.8 66.7 1.0 CD1 D:LEU956 4.9 91.4 1.0 N D:GLU560 4.9 67.8 1.0 C D:THR536 4.9 78.8 1.0

J.Zhang, S.Liu, J.Fan, R.Yan, B.Huang, F.Zhou, T.Yuan, J.Gong, Z.Huang, D.Jiang. Structural Basis of Human SLO2.2 Channel Gating and Modulation. Cell Rep V. 42 12858 2023.
ISSN: ESSN 2211-1247
PubMed: 37494189
DOI: 10.1016/J.CELREP.2023.112858