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Atomistry » Sodium » PDB 8cwg-8d7d » 8cza » |
Sodium in PDB 8cza: Crystal Structure of the First Bromodomain (BD1) of Human Brdt Bound to Gxh-IV-075Protein crystallography data
The structure of Crystal Structure of the First Bromodomain (BD1) of Human Brdt Bound to Gxh-IV-075, PDB code: 8cza
was solved by
A.Chan,
E.Schonbrunn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8cza:
The structure of Crystal Structure of the First Bromodomain (BD1) of Human Brdt Bound to Gxh-IV-075 also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Crystal Structure of the First Bromodomain (BD1) of Human Brdt Bound to Gxh-IV-075
(pdb code 8cza). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of the First Bromodomain (BD1) of Human Brdt Bound to Gxh-IV-075, PDB code: 8cza: Jump to Sodium binding site number: 1; 2; Sodium binding site 1 out of 2 in 8czaGo back to![]() ![]()
Sodium binding site 1 out
of 2 in the Crystal Structure of the First Bromodomain (BD1) of Human Brdt Bound to Gxh-IV-075
![]() Mono view ![]() Stereo pair view
Sodium binding site 2 out of 2 in 8czaGo back to![]() ![]()
Sodium binding site 2 out
of 2 in the Crystal Structure of the First Bromodomain (BD1) of Human Brdt Bound to Gxh-IV-075
![]() Mono view ![]() Stereo pair view
Reference:
X.Guan,
N.Cheryala,
R.M.Karim,
A.Chan,
N.Berndt,
J.Qi,
G.I.Georg,
E.Schonbrunn.
Bivalent Bet Bromodomain Inhibitors Confer Increased Potency and Selectivity For Brdt Via Protein Conformational Plasticity. J.Med.Chem. V. 65 10441 2022.
Page generated: Wed Oct 9 11:19:37 2024
ISSN: ISSN 0022-2623 PubMed: 35867655 DOI: 10.1021/ACS.JMEDCHEM.2C00453 |
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