Atomistry » Sodium » PDB 8cpt-8cwf » 8crl
Atomistry »
  Sodium »
    PDB 8cpt-8cwf »
      8crl »

Sodium in PDB 8crl: Crystal Structure of LPLA1 in Complex with the Inhibitor C3 (Listeria Monocytogenes)

Enzymatic activity of Crystal Structure of LPLA1 in Complex with the Inhibitor C3 (Listeria Monocytogenes)

All present enzymatic activity of Crystal Structure of LPLA1 in Complex with the Inhibitor C3 (Listeria Monocytogenes):
6.3.1.20;

Protein crystallography data

The structure of Crystal Structure of LPLA1 in Complex with the Inhibitor C3 (Listeria Monocytogenes), PDB code: 8crl was solved by J.-N.Dienemann, S.-Y.Chen, M.Hitzenberger, M.L.Sievert, S.M.Hacker, S.T.Prigge, M.Zacharias, M.Groll, S.A.Sieber, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 2.60
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 59.32, 74.27, 92.73, 90, 98.06, 90
R / Rfree (%) 23.5 / 27.3

Other elements in 8crl:

The structure of Crystal Structure of LPLA1 in Complex with the Inhibitor C3 (Listeria Monocytogenes) also contains other interesting chemical elements:

Calcium (Ca) 2 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the Crystal Structure of LPLA1 in Complex with the Inhibitor C3 (Listeria Monocytogenes) (pdb code 8crl). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of LPLA1 in Complex with the Inhibitor C3 (Listeria Monocytogenes), PDB code: 8crl:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in 8crl

Go back to Sodium Binding Sites List in 8crl
Sodium binding site 1 out of 2 in the Crystal Structure of LPLA1 in Complex with the Inhibitor C3 (Listeria Monocytogenes)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of LPLA1 in Complex with the Inhibitor C3 (Listeria Monocytogenes) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na404

b:76.4
occ:1.00
OE1 A:GLU197 3.2 53.6 1.0
O A:GLU192 3.6 71.4 1.0
CD A:GLU197 3.9 54.0 1.0
OE2 A:GLU197 3.9 54.0 1.0
C A:GLU192 4.8 73.0 1.0

Sodium binding site 2 out of 2 in 8crl

Go back to Sodium Binding Sites List in 8crl
Sodium binding site 2 out of 2 in the Crystal Structure of LPLA1 in Complex with the Inhibitor C3 (Listeria Monocytogenes)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of LPLA1 in Complex with the Inhibitor C3 (Listeria Monocytogenes) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na405

b:70.2
occ:1.00
OD1 A:ASP153 2.8 54.0 1.0
OD1 A:ASP187 3.2 69.0 1.0
ND2 A:ASN184 3.8 51.7 1.0
CG A:ASP153 4.0 55.6 1.0
CG A:ASP187 4.1 65.8 1.0
OG A:SER186 4.2 53.3 1.0
OD2 A:ASP187 4.3 66.4 1.0
OD2 A:ASP153 4.6 58.6 1.0
CG A:ASN184 4.6 50.7 1.0
CB A:ASN184 4.7 51.0 1.0
CA A:ASP153 5.0 53.4 1.0

Reference:

J.N.Dienemann, S.Y.Chen, M.Hitzenberger, M.L.Sievert, S.M.Hacker, S.T.Prigge, M.Zacharias, M.Groll, S.A.Sieber. A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angew.Chem.Int.Ed.Engl. 04533 2023.
ISSN: ESSN 1521-3773
PubMed: 37249408
DOI: 10.1002/ANIE.202304533
Page generated: Wed Oct 9 11:03:12 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy