Sodium in PDB 8c59: Cpg Specific M.Mpei Methyltransferase Crystallized in the Presence of 5-Bromocytosine (Converted to 5MC) and 5-Methylcytosine Containing Dsdna

The structure of Cpg Specific M.Mpei Methyltransferase Crystallized in the Presence of 5-Bromocytosine (Converted to 5MC) and 5-Methylcytosine Containing Dsdna, PDB code: 8c59 was solved by M.Wojciechowski, H.Czapinska, J.Krwawicz, D.Rafalski, M.Bochtler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.95 / 1.70
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	84.511, 84.511, 173.115, 90, 90, 90
R / Rfree (%)	16.7 / 19.3

The binding sites of Sodium atom in the Cpg Specific M.Mpei Methyltransferase Crystallized in the Presence of 5-Bromocytosine (Converted to 5MC) and 5-Methylcytosine Containing Dsdna (pdb code 8c59). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Cpg Specific M.Mpei Methyltransferase Crystallized in the Presence of 5-Bromocytosine (Converted to 5MC) and 5-Methylcytosine Containing Dsdna, PDB code: 8c59:

Sodium binding site 1 out of 1 in the Cpg Specific M.Mpei Methyltransferase Crystallized in the Presence of 5-Bromocytosine (Converted to 5MC) and 5-Methylcytosine Containing Dsdna


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Cpg Specific M.Mpei Methyltransferase Crystallized in the Presence of 5-Bromocytosine (Converted to 5MC) and 5-Methylcytosine Containing Dsdna within 5.0Å range: probe atom residue distance (Å) B Occ A:Na402 b:52.8 occ:1.00 O A:HOH662 2.2 59.7 1.0 O A:ASN93 2.4 41.9 1.0 O A:LYS90 2.4 45.6 1.0 O7 A:CIT410 2.4 55.0 0.8 O6 A:CIT410 2.5 54.6 0.8 O4 A:CIT410 2.6 54.3 0.8 C6 A:CIT410 3.3 56.3 0.8 C3 A:CIT410 3.4 56.7 0.8 C A:ASN93 3.4 41.9 1.0 C A:LYS90 3.6 45.3 1.0 C5 A:CIT410 3.6 56.2 0.8 O A:HOH644 3.7 57.5 1.0 C4 A:CIT410 4.0 57.2 0.8 O A:LYS91 4.1 42.1 0.5 CB A:ASN93 4.1 42.1 1.0 CA A:LYS91 4.1 43.1 0.5 C A:LYS91 4.1 41.8 0.5 CA A:ASN93 4.1 40.9 1.0 O A:LYS91 4.1 42.2 0.5 CA A:LYS91 4.2 43.4 0.5 C A:LYS91 4.2 41.9 0.5 CB A:ASN94 4.2 46.0 1.0 ND2 A:ASN94 4.2 48.7 1.0 N A:ASN93 4.2 39.6 1.0 O2 A:CIT410 4.3 57.2 0.8 N A:LYS91 4.3 43.8 0.5 N A:LYS91 4.3 44.0 0.5 O5 A:CIT410 4.4 56.3 0.8 N A:ASN94 4.5 42.5 1.0 O A:HOH713 4.5 65.8 1.0 CA A:LYS90 4.6 47.0 1.0 C2 A:CIT410 4.7 58.4 0.8 CG A:ASN94 4.7 47.6 1.0 CA A:ASN94 4.7 43.6 1.0 ND2 A:ASN93 4.8 45.6 1.0 O3 A:CIT410 4.8 57.5 0.8 C A:ILE92 4.8 39.2 1.0 N A:ILE92 4.8 40.2 1.0 NZ A:LYS91 4.9 50.4 0.5 CG A:ASN93 4.9 43.5 1.0 O A:ASN94 4.9 43.3 1.0 C1 A:CIT410 4.9 58.5 0.8 C A:ASN94 5.0 42.6 1.0

M.Wojciechowski, H.Czapinska, J.Krwawicz, D.Rafalski, M.Bochtler. Cytosine Analogues As Dna Methyltransferase Substrates and Inhibitors To Be Published.