|
Atomistry » Sodium » PDB 7zyq-8acy » 7zzt | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 7zyq-8acy » 7zzt » |
Sodium in PDB 7zzt: Ligand Binding to HDAC2Enzymatic activity of Ligand Binding to HDAC2
All present enzymatic activity of Ligand Binding to HDAC2:
3.5.1.98; Protein crystallography data
The structure of Ligand Binding to HDAC2, PDB code: 7zzt
was solved by
A.Cleasby,
D.Tisi,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7zzt:
The structure of Ligand Binding to HDAC2 also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Ligand Binding to HDAC2
(pdb code 7zzt). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Ligand Binding to HDAC2, PDB code: 7zzt: Jump to Sodium binding site number: 1; 2; 3; Sodium binding site 1 out of 3 in 7zztGo back to Sodium Binding Sites List in 7zzt
Sodium binding site 1 out
of 3 in the Ligand Binding to HDAC2
Mono view Stereo pair view
Sodium binding site 2 out of 3 in 7zztGo back to Sodium Binding Sites List in 7zzt
Sodium binding site 2 out
of 3 in the Ligand Binding to HDAC2
Mono view Stereo pair view
Sodium binding site 3 out of 3 in 7zztGo back to Sodium Binding Sites List in 7zzt
Sodium binding site 3 out
of 3 in the Ligand Binding to HDAC2
Mono view Stereo pair view
Reference:
E.Tamanini,
S.Miyamura,
I.M.Buck,
B.D.Cons,
L.Dawson,
C.East,
T.Futamura,
S.Goto,
C.Griffiths-Jones,
T.Hashimoto,
T.D.Heightman,
S.Ishikawa,
H.Ito,
Y.Kaneko,
T.Kawato,
K.Kondo,
N.Kurihara,
J.M.Mccarthy,
Y.Mori,
T.Nagase,
Y.Nakaishi,
J.Reeks,
A.Sato,
P.Schopf,
K.Tai,
T.Tamai,
D.Tisi,
A.J.Woolford.
Fragment-Based Discovery of A Novel, Brain Penetrant, Orally Active HDAC2 Inhibitor. Acs Med.Chem.Lett. V. 13 1591 2022.
Page generated: Wed Oct 9 10:21:41 2024
ISSN: ISSN 1948-5875 PubMed: 36262388 DOI: 10.1021/ACSMEDCHEMLETT.2C00272 |
Last articlesZn in 9JYWZn in 9IR4 Zn in 9IR3 Zn in 9GMX Zn in 9GMW Zn in 9JEJ Zn in 9ERF Zn in 9ERE Zn in 9EGV Zn in 9EGW |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |