Sodium in PDB 7uv0: Structure of the Sodium/Iodide Symporter (Nis) in Complex with Iodide and Sodium

The structure of Structure of the Sodium/Iodide Symporter (Nis) in Complex with Iodide and Sodium also contains other interesting chemical elements:

Iodine

(I)

1 atom

The binding sites of Sodium atom in the Structure of the Sodium/Iodide Symporter (Nis) in Complex with Iodide and Sodium (pdb code 7uv0). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Structure of the Sodium/Iodide Symporter (Nis) in Complex with Iodide and Sodium, PDB code: 7uv0:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Structure of the Sodium/Iodide Symporter (Nis) in Complex with Iodide and Sodium


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structure of the Sodium/Iodide Symporter (Nis) in Complex with Iodide and Sodium within 5.0Å range: probe atom residue distance (Å) B Occ A:Na701 b:27.0 occ:1.00 NE2 A:GLN72 2.9 43.0 1.0 CZ A:PHE417 3.3 35.3 1.0 CE2 A:PHE417 3.3 38.8 1.0 OG A:SER416 3.5 27.4 1.0 CE1 A:PHE417 3.7 32.5 1.0 CE A:MET258 3.7 50.5 1.0 OH A:TYR144 3.7 42.5 1.0 CD2 A:PHE417 3.8 36.0 1.0 CE2 A:TYR144 4.0 32.8 1.0 CD1 A:PHE417 4.1 38.3 1.0 CD A:GLN72 4.1 46.3 1.0 CG A:PHE417 4.1 36.5 1.0 NA A:NA702 4.3 30.1 1.0 CB A:SER416 4.3 20.8 1.0 CZ A:TYR144 4.4 38.8 1.0 OE1 A:GLN72 4.5 44.7 1.0 N A:PHE417 4.7 30.6 1.0 SD A:MET258 4.8 53.3 1.0 CG1 A:VAL71 4.8 42.5 1.0 CH2 A:TRP255 4.9 43.2 1.0 CD1 A:LEU413 4.9 41.0 1.0 O A:LEU413 4.9 40.9 1.0

Sodium binding site 2 out of 2 in the Structure of the Sodium/Iodide Symporter (Nis) in Complex with Iodide and Sodium


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Structure of the Sodium/Iodide Symporter (Nis) in Complex with Iodide and Sodium within 5.0Å range: probe atom residue distance (Å) B Occ A:Na702 b:30.1 occ:1.00 OE1 A:GLN72 2.2 44.7 1.0 OG A:SER69 2.6 46.1 1.0 OH A:TYR144 2.7 42.5 1.0 CD A:GLN72 3.2 46.3 1.0 NE2 A:GLN72 3.5 43.0 1.0 CB A:VAL71 3.5 39.9 1.0 CZ A:TYR144 3.8 38.8 1.0 N A:SER69 3.9 42.5 1.0 CB A:SER69 4.0 41.9 1.0 CG1 A:VAL71 4.0 42.5 1.0 CG2 A:VAL71 4.1 37.1 1.0 C A:PHE67 4.2 55.6 1.0 CA A:PHE67 4.2 58.8 1.0 NA A:NA701 4.3 27.0 1.0 N A:GLN72 4.4 39.7 1.0 O A:PHE67 4.4 46.9 1.0 CE1 A:TYR144 4.4 38.9 1.0 CA A:SER69 4.5 40.7 1.0 CG2 A:VAL148 4.5 26.6 1.0 N A:MET68 4.5 53.8 1.0 CB A:PHE67 4.6 51.3 1.0 CG A:GLN72 4.6 43.2 1.0 CA A:VAL71 4.6 37.5 1.0 CE2 A:TYR144 4.7 32.8 1.0 N A:VAL71 4.7 32.3 1.0 CD1 A:PHE67 4.8 55.6 1.0 C A:VAL71 4.9 38.6 1.0 C A:SER69 4.9 43.1 1.0 C A:MET68 4.9 49.0 1.0 O A:SER69 5.0 46.2 1.0 CA A:MET68 5.0 49.3 1.0

S.Ravera, J.P.Nicola, G.Salazar-De Simone, F.J.Sigworth, E.Karakas, L.M.Amzel, M.A.Bianchet, N.Carrasco. Structural Insights Into the Mechanism of the Sodium/Iodide Symporter. Nature V. 612 795 2022.
ISSN: ESSN 1476-4687
PubMed: 36517601
DOI: 10.1038/S41586-022-05530-2