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Atomistry » Sodium » PDB 7stu-7tpm » 7tnh | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 7stu-7tpm » 7tnh » |
Sodium in PDB 7tnh: Crystal Structure of CSF1R Kinase Domain in Complex with Dp-6233Enzymatic activity of Crystal Structure of CSF1R Kinase Domain in Complex with Dp-6233
All present enzymatic activity of Crystal Structure of CSF1R Kinase Domain in Complex with Dp-6233:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of CSF1R Kinase Domain in Complex with Dp-6233, PDB code: 7tnh
was solved by
T.E.Edwards,
T.L.Arakaki,
L.Chun,
D.L.Flynn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7tnh:
The structure of Crystal Structure of CSF1R Kinase Domain in Complex with Dp-6233 also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Crystal Structure of CSF1R Kinase Domain in Complex with Dp-6233
(pdb code 7tnh). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of CSF1R Kinase Domain in Complex with Dp-6233, PDB code: 7tnh: Sodium binding site 1 out of 1 in 7tnhGo back to Sodium Binding Sites List in 7tnh
Sodium binding site 1 out
of 1 in the Crystal Structure of CSF1R Kinase Domain in Complex with Dp-6233
Mono view Stereo pair view
Reference:
T.M.Caldwell,
M.D.Kaufman,
S.C.Wise,
Y.Mi Ahn,
M.M.Hood,
W.P.Lu,
W.C.Patt,
T.Samarakoon,
L.Vogeti,
S.Vogeti,
K.M.Yates,
S.L.Bulfer,
B.Le Bourdonnec,
B.D.Smith,
D.L.Flynn.
Discovery of Acyl Ureas As Highly Selective Small Molecule CSF1R Kinase Inhibitors. Bioorg.Med.Chem.Lett. V. 74 28929 2022.
Page generated: Fri Apr 7 16:32:48 2023
ISSN: ESSN 1464-3405 PubMed: 35961461 DOI: 10.1016/J.BMCL.2022.128929 |
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