Sodium in PDB 7rm3: Antibody 2E10.E9 in Complex with P. Vivax Csp Peptide Angagnqpgangagnqpgangaggqaa

The structure of Antibody 2E10.E9 in Complex with P. Vivax Csp Peptide Angagnqpgangagnqpgangaggqaa, PDB code: 7rm3 was solved by I.Kucharska, D.Ivanochko, J.P.Julien, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.48 / 2.68
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	56.404, 144.436, 60.471, 90, 102.83, 90
R / Rfree (%)	20.7 / 23.9

The binding sites of Sodium atom in the Antibody 2E10.E9 in Complex with P. Vivax Csp Peptide Angagnqpgangagnqpgangaggqaa (pdb code 7rm3). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Antibody 2E10.E9 in Complex with P. Vivax Csp Peptide Angagnqpgangagnqpgangaggqaa, PDB code: 7rm3:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Antibody 2E10.E9 in Complex with P. Vivax Csp Peptide Angagnqpgangagnqpgangaggqaa


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Antibody 2E10.E9 in Complex with P. Vivax Csp Peptide Angagnqpgangagnqpgangaggqaa within 5.0Å range: probe atom residue distance (Å) B Occ B:Na301 b:47.7 occ:1.00 OG1 B:THR178 3.1 45.0 1.0 CB B:THR178 3.8 42.5 1.0 OG A:SER177 3.9 47.4 1.0 CG2 B:THR178 4.2 42.9 1.0 CD1 A:LEU141 4.2 42.0 1.0 OG A:SER179 4.4 70.9 1.0 CG2 A:VAL169 4.4 65.9 1.0 N A:LEU178 4.4 38.3 1.0 C A:SER177 4.5 35.9 1.0 O A:SER177 4.5 38.0 1.0 C A:LEU178 4.5 47.5 1.0 CB A:SER177 4.5 37.8 1.0 CA A:LEU178 4.6 42.9 1.0 O A:LEU178 4.7 53.7 1.0 N A:SER179 4.8 47.9 1.0 CB A:SER179 4.9 55.0 1.0

Sodium binding site 2 out of 2 in the Antibody 2E10.E9 in Complex with P. Vivax Csp Peptide Angagnqpgangagnqpgangaggqaa


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Antibody 2E10.E9 in Complex with P. Vivax Csp Peptide Angagnqpgangagnqpgangaggqaa within 5.0Å range: probe atom residue distance (Å) B Occ D:Na301 b:53.0 occ:1.00 OG1 D:THR178 3.3 37.5 1.0 OG C:SER177 3.7 41.2 1.0 CB D:THR178 4.1 46.0 1.0 N C:LEU178 4.1 31.9 1.0 CD1 C:LEU141 4.2 48.8 1.0 C C:LEU178 4.2 41.0 1.0 OG C:SER179 4.2 52.2 1.0 CA C:LEU178 4.3 30.6 1.0 C C:SER177 4.3 37.1 1.0 O C:LEU178 4.4 49.6 1.0 O C:SER177 4.4 34.5 1.0 CB C:SER177 4.4 42.9 1.0 N C:SER179 4.5 34.7 1.0 CG2 D:THR178 4.6 39.2 1.0 CG2 C:VAL169 4.6 67.3 1.0 OG D:SER176 4.7 39.9 1.0 CB C:SER179 4.8 34.5 1.0

I.Kucharska, L.Hossain, D.Ivanochko, Q.Yang, J.L.Rubinstein, R.Pomes, J.P.Julien. Structural Basis of Plasmodium Vivax Inhibition By Antibodies Binding to the Circumsporozoite Protein Repeats. Elife V. 11 2022.
ISSN: ESSN 2050-084X
PubMed: 35023832
DOI: 10.7554/ELIFE.72908