Sodium in PDB 7rjo: Crystal Structure of Human Bromodomain Containing Protein 4 (BRD4) in Complex with Hnrnpk

The structure of Crystal Structure of Human Bromodomain Containing Protein 4 (BRD4) in Complex with Hnrnpk, PDB code: 7rjo was solved by E.Fedorov, K.Islam, A.Ghosh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.23 / 1.38
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	48.454, 52.08, 53.325, 90, 90, 90
R / Rfree (%)	17.6 / 19.8

The binding sites of Sodium atom in the Crystal Structure of Human Bromodomain Containing Protein 4 (BRD4) in Complex with Hnrnpk (pdb code 7rjo). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Human Bromodomain Containing Protein 4 (BRD4) in Complex with Hnrnpk, PDB code: 7rjo:

Sodium binding site 1 out of 1 in the Crystal Structure of Human Bromodomain Containing Protein 4 (BRD4) in Complex with Hnrnpk


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Human Bromodomain Containing Protein 4 (BRD4) in Complex with Hnrnpk within 5.0Å range: probe atom residue distance (Å) B Occ A:Na201 b:27.4 occ:1.00 HH33 B:ALY60 2.6 17.2 1.0 O A:MET132 2.7 13.3 1.0 O A:HOH343 2.7 18.8 1.0 O A:HOH316 2.8 14.3 1.0 HB2 A:CYS136 2.8 13.4 1.0 HG3 A:MET132 3.0 18.5 1.0 HB2 A:ASN135 3.2 17.5 1.0 H A:CYS136 3.4 15.2 1.0 HD1 A:PHE83 3.4 18.6 1.0 HH31 B:ALY60 3.5 17.2 1.0 CH3 B:ALY60 3.5 14.4 1.0 HE1 A:PHE83 3.6 17.7 1.0 HG2 A:MET132 3.6 18.5 1.0 HA A:MET132 3.7 15.3 1.0 C A:MET132 3.7 13.5 1.0 CG A:MET132 3.7 15.4 1.0 N A:CYS136 3.7 12.7 1.0 CB A:CYS136 3.8 11.1 1.0 HH A:TYR97 3.8 23.6 1.0 O A:HOH362 3.9 23.5 1.0 HA A:CYS136 4.0 15.4 1.0 CB A:ASN135 4.1 14.6 1.0 CA A:CYS136 4.1 12.8 1.0 CD1 A:PHE83 4.1 15.4 1.0 HB3 A:ASN135 4.1 17.5 1.0 CA A:MET132 4.1 12.8 1.0 CE1 A:PHE83 4.2 14.7 1.0 O A:MET105 4.2 17.2 1.0 HB3 A:CYS136 4.3 13.4 1.0 HH32 B:ALY60 4.3 17.2 1.0 OH A:TYR97 4.3 19.6 1.0 HD22 A:ASN135 4.3 18.9 1.0 OH B:ALY60 4.4 15.7 1.0 CH B:ALY60 4.4 15.6 1.0 C A:ASN135 4.5 13.6 1.0 CB A:MET132 4.5 13.5 1.0 HA A:PHE133 4.6 15.2 1.0 SG A:CYS136 4.8 14.6 1.0 CA A:ASN135 4.8 12.4 1.0 N A:PHE133 4.8 11.6 1.0 H A:ASN135 4.9 15.3 1.0 HG23 A:VAL87 4.9 27.3 1.0 HG A:CYS136 4.9 17.6 1.0 O A:HOH366 4.9 15.9 1.0 HB2 A:MET132 4.9 16.2 1.0 HG21 A:VAL87 4.9 27.3 1.0

S.Wagner, E.Fedorov, B.Sudhamalla, H.N.Jnawali, R.Debiec, A.Ghosh, K.Islam. Uncovering the Bromodomain Interactome Using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization Biorxiv 2021.
DOI: 10.1101/2021.07.28.453719