Sodium in PDB 7qoa: Structure of Codb, A Cytosine Transporter in An Outward-Facing Conformation
Protein crystallography data
The structure of Structure of Codb, A Cytosine Transporter in An Outward-Facing Conformation, PDB code: 7qoa
was solved by
C.E.Hatton,
A.D.Cameron,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
73.16 /
2.40
|
Space group
|
C 2 2 21
|
Cell size a, b, c (Å), α, β, γ (°)
|
108.246,
209.027,
102.452,
90,
90,
90
|
R / Rfree (%)
|
21.8 /
26.5
|
Sodium Binding Sites:
The binding sites of Sodium atom in the Structure of Codb, A Cytosine Transporter in An Outward-Facing Conformation
(pdb code 7qoa). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the
Structure of Codb, A Cytosine Transporter in An Outward-Facing Conformation, PDB code: 7qoa:
Jump to Sodium binding site number:
1;
2;
Sodium binding site 1 out
of 2 in 7qoa
Go back to
Sodium Binding Sites List in 7qoa
Sodium binding site 1 out
of 2 in the Structure of Codb, A Cytosine Transporter in An Outward-Facing Conformation
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 1 of Structure of Codb, A Cytosine Transporter in An Outward-Facing Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na506
b:35.4
occ:1.00
|
OG1
|
A:THR279
|
2.3
|
28.7
|
1.0
|
O
|
A:ASN275
|
2.3
|
38.2
|
1.0
|
O
|
A:GLY29
|
2.4
|
37.7
|
1.0
|
O
|
A:PHE32
|
2.4
|
35.4
|
1.0
|
OG1
|
A:THR278
|
2.5
|
34.7
|
1.0
|
N
|
A:THR279
|
2.9
|
35.9
|
1.0
|
CB
|
A:THR279
|
3.2
|
33.8
|
1.0
|
C
|
A:PHE32
|
3.4
|
37.1
|
1.0
|
C
|
A:ASN275
|
3.4
|
35.2
|
1.0
|
CA
|
A:THR279
|
3.4
|
34.9
|
1.0
|
CB
|
A:THR278
|
3.5
|
35.1
|
1.0
|
C
|
A:GLY29
|
3.5
|
35.7
|
1.0
|
C
|
A:THR278
|
3.7
|
36.0
|
1.0
|
O
|
A:LEU30
|
3.8
|
38.1
|
1.0
|
CA
|
A:ASN275
|
3.8
|
33.1
|
1.0
|
CA
|
A:THR278
|
4.0
|
36.6
|
1.0
|
CA
|
A:PHE32
|
4.2
|
31.7
|
1.0
|
C
|
A:LEU30
|
4.2
|
36.9
|
1.0
|
N
|
A:PHE33
|
4.2
|
35.5
|
1.0
|
N
|
A:PHE32
|
4.3
|
35.4
|
1.0
|
CA
|
A:PHE33
|
4.3
|
35.9
|
1.0
|
CA
|
A:GLY29
|
4.3
|
31.4
|
1.0
|
CB
|
A:PHE32
|
4.3
|
34.8
|
1.0
|
CB
|
A:PHE33
|
4.4
|
26.9
|
1.0
|
N
|
A:THR278
|
4.4
|
34.0
|
1.0
|
N
|
A:LEU30
|
4.4
|
36.9
|
1.0
|
CA
|
A:LEU30
|
4.4
|
35.0
|
1.0
|
CB
|
A:ASN275
|
4.5
|
38.2
|
1.0
|
O
|
A:LEU274
|
4.5
|
36.5
|
1.0
|
N
|
A:ILE276
|
4.5
|
34.3
|
1.0
|
CD1
|
A:PHE33
|
4.6
|
26.4
|
1.0
|
CG2
|
A:THR279
|
4.6
|
27.5
|
1.0
|
O
|
A:THR278
|
4.6
|
33.8
|
1.0
|
CG2
|
A:THR278
|
4.8
|
28.7
|
1.0
|
OD1
|
A:ASN275
|
4.8
|
38.5
|
1.0
|
O
|
A:ILE276
|
4.9
|
31.5
|
1.0
|
C
|
A:THR279
|
4.9
|
33.5
|
1.0
|
CG
|
A:PHE33
|
4.9
|
30.2
|
1.0
|
CA
|
A:ILE276
|
4.9
|
34.8
|
1.0
|
O
|
A:LEU28
|
4.9
|
36.9
|
1.0
|
C
|
A:ILE276
|
5.0
|
34.4
|
1.0
|
N
|
A:THR31
|
5.0
|
33.7
|
1.0
|
C
|
A:THR31
|
5.0
|
33.5
|
1.0
|
|
Sodium binding site 2 out
of 2 in 7qoa
Go back to
Sodium Binding Sites List in 7qoa
Sodium binding site 2 out
of 2 in the Structure of Codb, A Cytosine Transporter in An Outward-Facing Conformation
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 2 of Structure of Codb, A Cytosine Transporter in An Outward-Facing Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Na505
b:35.9
occ:1.00
|
O
|
B:GLY29
|
2.2
|
40.2
|
1.0
|
O
|
B:ASN275
|
2.3
|
36.7
|
1.0
|
OG1
|
B:THR279
|
2.3
|
33.9
|
1.0
|
OG1
|
B:THR278
|
2.4
|
36.7
|
1.0
|
O
|
B:PHE32
|
2.4
|
32.8
|
1.0
|
N
|
B:THR279
|
3.0
|
37.8
|
1.0
|
C
|
B:ASN275
|
3.2
|
35.5
|
1.0
|
CB
|
B:THR279
|
3.4
|
34.4
|
1.0
|
C
|
B:PHE32
|
3.4
|
37.1
|
1.0
|
C
|
B:GLY29
|
3.4
|
36.7
|
1.0
|
CB
|
B:THR278
|
3.4
|
34.0
|
1.0
|
CA
|
B:THR279
|
3.6
|
35.2
|
1.0
|
CA
|
B:ASN275
|
3.7
|
33.2
|
1.0
|
C
|
B:THR278
|
3.7
|
37.9
|
1.0
|
CA
|
B:THR278
|
4.0
|
36.8
|
1.0
|
O
|
B:LEU30
|
4.1
|
40.7
|
1.0
|
CA
|
B:PHE32
|
4.2
|
39.2
|
1.0
|
CB
|
B:PHE32
|
4.2
|
35.2
|
1.0
|
CA
|
B:GLY29
|
4.2
|
35.8
|
1.0
|
N
|
B:THR278
|
4.2
|
33.8
|
1.0
|
N
|
B:PHE32
|
4.3
|
36.9
|
1.0
|
O
|
B:LEU274
|
4.3
|
33.1
|
1.0
|
N
|
B:PHE33
|
4.3
|
33.7
|
1.0
|
C
|
B:LEU30
|
4.4
|
39.2
|
1.0
|
N
|
B:ILE276
|
4.4
|
37.9
|
1.0
|
N
|
B:LEU30
|
4.4
|
37.6
|
1.0
|
CB
|
B:ASN275
|
4.4
|
29.6
|
1.0
|
CA
|
B:PHE33
|
4.5
|
32.5
|
1.0
|
CA
|
B:LEU30
|
4.5
|
41.1
|
1.0
|
CB
|
B:PHE33
|
4.5
|
32.8
|
1.0
|
CD1
|
B:PHE33
|
4.7
|
28.2
|
1.0
|
O
|
B:THR278
|
4.7
|
36.4
|
1.0
|
CG2
|
B:THR279
|
4.7
|
33.3
|
1.0
|
CG2
|
B:THR278
|
4.7
|
34.5
|
1.0
|
OD1
|
B:ASN275
|
4.8
|
34.9
|
1.0
|
CA
|
B:ILE276
|
4.8
|
33.2
|
1.0
|
N
|
B:ASN275
|
4.9
|
32.1
|
1.0
|
O
|
B:LEU28
|
5.0
|
34.0
|
1.0
|
C
|
B:ILE276
|
5.0
|
33.5
|
1.0
|
|
Reference:
C.E.Hatton,
D.H.Brotherton,
M.Spencer,
A.D.Cameron.
Structure of Cytosine Transport Protein Codb Provides Insight Into Nucleobase-Cation Symporter 1 Mechanism. Embo J. V. 41 10527 2022.
ISSN: ESSN 1460-2075
PubMed: 35775318
DOI: 10.15252/EMBJ.2021110527
Page generated: Wed Oct 9 08:23:17 2024
|