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Atomistry » Sodium » PDB 7nuz-7oi2 » 7o5z » |
Sodium in PDB 7o5z: Human Phosphomannomutase 2 (PMM2) with Mutation T237M in Apo StateEnzymatic activity of Human Phosphomannomutase 2 (PMM2) with Mutation T237M in Apo State
All present enzymatic activity of Human Phosphomannomutase 2 (PMM2) with Mutation T237M in Apo State:
5.4.2.8; Protein crystallography data
The structure of Human Phosphomannomutase 2 (PMM2) with Mutation T237M in Apo State, PDB code: 7o5z
was solved by
S.Ramon-Maiques,
A.Briso-Montiano,
F.Del Cano-Ochoa,
A.Vilas,
B.Perez,
V.Rubio,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7o5z:
The structure of Human Phosphomannomutase 2 (PMM2) with Mutation T237M in Apo State also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Human Phosphomannomutase 2 (PMM2) with Mutation T237M in Apo State
(pdb code 7o5z). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Human Phosphomannomutase 2 (PMM2) with Mutation T237M in Apo State, PDB code: 7o5z: Jump to Sodium binding site number: 1; 2; Sodium binding site 1 out of 2 in 7o5zGo back to![]() ![]()
Sodium binding site 1 out
of 2 in the Human Phosphomannomutase 2 (PMM2) with Mutation T237M in Apo State
![]() Mono view ![]() Stereo pair view
Sodium binding site 2 out of 2 in 7o5zGo back to![]() ![]()
Sodium binding site 2 out
of 2 in the Human Phosphomannomutase 2 (PMM2) with Mutation T237M in Apo State
![]() Mono view ![]() Stereo pair view
Reference:
A.Briso-Montiano,
F.Del Cano-Ochoa,
A.Vilas,
A.Velazquez-Campoy,
V.Rubio,
B.Perez,
S.Ramon-Maiques.
Insight on Molecular Pathogenesis and Pharmacochaperoning Potential in Phosphomannomutase 2 Deficiency, Provided By Novel Human Phosphomannomutase 2 Structures. J Inherit Metab Dis V. 45 318 2022.
Page generated: Fri Apr 7 15:22:53 2023
ISSN: ISSN 1573-2665 PubMed: 34859900 DOI: 10.1002/JIMD.12461 |
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