Sodium in PDB 7nge: Crystal Structure of L-Trp/Indoleamine 2,3-Dioxygenagse 1 (HIDO1) Complex with the Jk-Loop Refined in the Closed Conformation

Enzymatic activity of Crystal Structure of L-Trp/Indoleamine 2,3-Dioxygenagse 1 (HIDO1) Complex with the Jk-Loop Refined in the Closed Conformation

All present enzymatic activity of Crystal Structure of L-Trp/Indoleamine 2,3-Dioxygenagse 1 (HIDO1) Complex with the Jk-Loop Refined in the Closed Conformation:
1.13.11.52;

Protein crystallography data

The structure of Crystal Structure of L-Trp/Indoleamine 2,3-Dioxygenagse 1 (HIDO1) Complex with the Jk-Loop Refined in the Closed Conformation, PDB code: 7nge was solved by M.Mirgaux, J.Wouters, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.87 / 2.30
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 81.36, 114.67, 219.67, 90, 90, 90
R / Rfree (%) 21.5 / 27.1

Other elements in 7nge:

The structure of Crystal Structure of L-Trp/Indoleamine 2,3-Dioxygenagse 1 (HIDO1) Complex with the Jk-Loop Refined in the Closed Conformation also contains other interesting chemical elements:

Chlorine (Cl) 1 atom
Iron (Fe) 4 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the Crystal Structure of L-Trp/Indoleamine 2,3-Dioxygenagse 1 (HIDO1) Complex with the Jk-Loop Refined in the Closed Conformation (pdb code 7nge). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of L-Trp/Indoleamine 2,3-Dioxygenagse 1 (HIDO1) Complex with the Jk-Loop Refined in the Closed Conformation, PDB code: 7nge:

Sodium binding site 1 out of 1 in 7nge

Go back to Sodium Binding Sites List in 7nge
Sodium binding site 1 out of 1 in the Crystal Structure of L-Trp/Indoleamine 2,3-Dioxygenagse 1 (HIDO1) Complex with the Jk-Loop Refined in the Closed Conformation


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of L-Trp/Indoleamine 2,3-Dioxygenagse 1 (HIDO1) Complex with the Jk-Loop Refined in the Closed Conformation within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na512

b:67.5
occ:1.00
 OE1 A:GLU202 2.6 72.1 1.0
O A:SER176 3.0 63.7 1.0
CD A:GLU202 3.5 72.1 1.0
CE A:LYS179 3.5 68.2 1.0
CG A:GLU202 3.6 59.7 1.0
SG A:CYS206 3.7 60.5 1.0
C A:SER176 4.0 61.8 1.0
CG2 A:VAL180 4.0 54.5 1.0
CB A:SER176 4.2 55.4 1.0
NZ A:LYS179 4.3 75.4 1.0
CA A:SER176 4.5 60.8 1.0
CG A:LYS179 4.6 67.3 1.0
OE2 A:GLU202 4.7 67.8 1.0
CD A:LYS179 4.7 67.1 1.0
N A:ALA177 5.0 55.2 1.0

Reference:

M.Mirgaux, L.Leherte, J.Wouters. Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of An Exo Site International Journal of 2021TRYPTOPHAN Research.
DOI: 10.1177/11786469211052964
Page generated: Tue Oct 8 18:09:43 2024

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