Sodium in PDB 7lsv: Non-Kinase Domain of Legionella Effector Protein Kinase LEGK2

All present enzymatic activity of Non-Kinase Domain of Legionella Effector Protein Kinase LEGK2:
2.7.11.17;

The structure of Non-Kinase Domain of Legionella Effector Protein Kinase LEGK2, PDB code: 7lsv was solved by K.A.Beyrakhova, K.Van Straaten, M.Cygler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.77 / 1.58
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	43.31, 54.75, 71.65, 90, 107.04, 90
R / Rfree (%)	17.7 / 20.5

The binding sites of Sodium atom in the Non-Kinase Domain of Legionella Effector Protein Kinase LEGK2 (pdb code 7lsv). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Non-Kinase Domain of Legionella Effector Protein Kinase LEGK2, PDB code: 7lsv:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Non-Kinase Domain of Legionella Effector Protein Kinase LEGK2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Non-Kinase Domain of Legionella Effector Protein Kinase LEGK2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na501 b:35.1 occ:1.00 OD1 A:ASN438 2.3 23.6 1.0 O A:HOH702 2.3 40.2 1.0 OG A:SER440 2.5 25.7 1.0 OG A:SER390 2.6 22.4 1.0 O A:HOH663 2.9 41.1 1.0 O A:HOH690 3.1 26.8 1.0 CG A:ASN438 3.4 22.0 1.0 CB A:SER390 3.5 17.7 1.0 CB A:SER440 3.6 27.1 1.0 O A:HOH616 3.6 35.2 1.0 ND2 A:ASN438 3.8 22.2 1.0 O A:HOH642 4.0 27.4 1.0 O A:HOH635 4.1 32.0 1.0 N A:SER440 4.6 24.1 1.0 CA A:SER440 4.6 24.6 1.0 CB A:ASN438 4.7 20.8 1.0 O A:HOH622 4.7 32.4 1.0 OD1 A:ASP387 4.7 25.2 1.0 CA A:SER390 4.7 14.5 1.0 CA A:ASN438 4.9 19.1 1.0

Sodium binding site 2 out of 2 in the Non-Kinase Domain of Legionella Effector Protein Kinase LEGK2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Non-Kinase Domain of Legionella Effector Protein Kinase LEGK2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Na501 b:27.0 occ:1.00 O B:LYS411 2.3 49.5 1.0 O B:HOH677 2.3 26.4 1.0 O B:HOH682 2.4 31.3 1.0 O B:HOH687 2.4 34.9 1.0 O B:ASP408 2.4 20.5 1.0 O B:HOH627 2.5 25.9 1.0 C B:LYS411 3.4 53.4 1.0 C B:ASP408 3.5 20.5 1.0 N B:LYS411 4.0 50.2 1.0 CA B:LYS411 4.1 52.5 1.0 O B:ASN409 4.1 23.1 1.0 O B:HOH694 4.1 47.2 1.0 CB B:LYS411 4.2 51.5 1.0 C B:ASN409 4.2 25.4 1.0 CA B:ASN409 4.2 20.3 1.0 N B:ASN409 4.3 19.7 1.0 CB B:ASP408 4.4 21.6 1.0 CA B:ASP408 4.5 20.4 1.0 N B:ASN412 4.5 59.0 1.0 OD1 B:ASN412 4.6 66.8 1.0 ND2 B:ASN363 4.7 23.6 1.0 CA B:ASN412 4.8 63.8 1.0 N B:SER410 4.9 30.1 1.0

K.A.Beyrakhova, K.Van Straaten, M.Cygler. Non-Kinase Domain of Legionella Effector Protein Kinase LEGK2 To Be Published.