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Atomistry » Sodium » PDB 7l2s-7lpa » 7la9 » |
Sodium in PDB 7la9: Crystal Structure of the First Bromodomain (BD1) of Human BRD4 (BRD4- 1) in Complex with Bivalent Inhibitor Nc-III-49-1Protein crystallography data
The structure of Crystal Structure of the First Bromodomain (BD1) of Human BRD4 (BRD4- 1) in Complex with Bivalent Inhibitor Nc-III-49-1, PDB code: 7la9
was solved by
M.R.Karim,
E.Schonbrunn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7la9:
The structure of Crystal Structure of the First Bromodomain (BD1) of Human BRD4 (BRD4- 1) in Complex with Bivalent Inhibitor Nc-III-49-1 also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Crystal Structure of the First Bromodomain (BD1) of Human BRD4 (BRD4- 1) in Complex with Bivalent Inhibitor Nc-III-49-1
(pdb code 7la9). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of the First Bromodomain (BD1) of Human BRD4 (BRD4- 1) in Complex with Bivalent Inhibitor Nc-III-49-1, PDB code: 7la9: Sodium binding site 1 out of 1 in 7la9Go back to![]() ![]()
Sodium binding site 1 out
of 1 in the Crystal Structure of the First Bromodomain (BD1) of Human BRD4 (BRD4- 1) in Complex with Bivalent Inhibitor Nc-III-49-1
![]() Mono view ![]() Stereo pair view
Reference:
X.Guan,
N.Cheryala,
R.M.Karim,
A.Chan,
N.Berndt,
J.Qi,
G.I.Georg,
E.Schonbrunn.
Bivalent Bet Bromodomain Inhibitors Confer Increased Potency and Selectivity For Brdt Via Protein Conformational Plasticity. J.Med.Chem. V. 65 10441 2022.
Page generated: Fri Apr 7 14:57:47 2023
ISSN: ISSN 0022-2623 PubMed: 35867655 DOI: 10.1021/ACS.JMEDCHEM.2C00453 |
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