Sodium in PDB 7l2m: Cryo-Em Structure of Dktx/Rtx-Bound Full-Length TRPV1

The binding sites of Sodium atom in the Cryo-Em Structure of Dktx/Rtx-Bound Full-Length TRPV1 (pdb code 7l2m). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Cryo-Em Structure of Dktx/Rtx-Bound Full-Length TRPV1, PDB code: 7l2m:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the Cryo-Em Structure of Dktx/Rtx-Bound Full-Length TRPV1


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Cryo-Em Structure of Dktx/Rtx-Bound Full-Length TRPV1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na902 b:65.3 occ:1.00 OD2 D:ASP646 4.5 73.3 1.0 OD2 C:ASP646 4.6 75.1 1.0 OD2 B:ASP646 4.6 72.1 1.0 O A:MET644 4.8 60.6 1.0 OD1 A:ASP646 4.8 71.8 1.0 O D:MET644 4.9 61.4 1.0 O B:MET644 4.9 60.3 1.0 O C:MET644 4.9 59.6 1.0

Sodium binding site 2 out of 3 in the Cryo-Em Structure of Dktx/Rtx-Bound Full-Length TRPV1


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Cryo-Em Structure of Dktx/Rtx-Bound Full-Length TRPV1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Na902 b:25.4 occ:1.00 OH A:TYR671 4.4 50.5 1.0 OH D:TYR671 4.5 51.0 1.0 OH B:TYR671 4.5 46.2 1.0 OH C:TYR671 4.5 49.4 1.0 O C:GLY643 5.0 56.9 1.0

Sodium binding site 3 out of 3 in the Cryo-Em Structure of Dktx/Rtx-Bound Full-Length TRPV1


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Cryo-Em Structure of Dktx/Rtx-Bound Full-Length TRPV1 within 5.0Å range:

K.Zhang, D.Julius, Y.Cheng. Structural Snapshots of TRPV1 Reveal Mechanism of Polymodal Functionality. Cell 2021.
ISSN: ISSN 1097-4172
PubMed: 34496225
DOI: 10.1016/J.CELL.2021.08.012