Sodium in PDB 7k89: Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Emixustat and Palmitate

All present enzymatic activity of Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Emixustat and Palmitate:
3.1.1.64; 5.3.3.22;

The structure of Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Emixustat and Palmitate, PDB code: 7k89 was solved by P.D.Kiser, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.84 / 2.15
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	175.695, 175.695, 86.214, 90, 90, 120
R / Rfree (%)	18.9 / 21.7

The structure of Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Emixustat and Palmitate also contains other interesting chemical elements:

Iron	(Fe)	2 atoms
Fluorine	(F)	2 atoms

The binding sites of Sodium atom in the Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Emixustat and Palmitate (pdb code 7k89). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Emixustat and Palmitate, PDB code: 7k89:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Emixustat and Palmitate


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Emixustat and Palmitate within 5.0Å range: probe atom residue distance (Å) B Occ A:Na604 b:74.2 occ:1.00 O5 A:PG4603 2.6 59.4 1.0 O1 A:PG4603 2.7 70.6 1.0 O3 A:PG4603 3.0 63.1 1.0 O2 A:PG4603 3.1 68.8 1.0 O A:GLN461 3.2 45.6 1.0 O4 A:PG4603 3.3 61.0 1.0 C6 A:PG4603 3.7 62.0 1.0 C1 A:PG4603 3.8 69.9 1.0 C3 A:PG4603 3.8 66.8 1.0 C8 A:PG4603 3.8 60.0 1.0 C2 A:PG4603 3.8 69.8 1.0 C7 A:PG4603 3.9 60.1 1.0 C5 A:PG4603 4.0 62.4 1.0 C4 A:PG4603 4.0 65.1 1.0 C A:GLN461 4.4 44.8 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Emixustat and Palmitate


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Emixustat and Palmitate within 5.0Å range: probe atom residue distance (Å) B Occ B:Na604 b:60.5 occ:1.00 O B:GLN461 2.4 41.4 1.0 O B:HOH1000 2.4 55.5 1.0 O5 B:PG4603 2.5 54.6 1.0 O1 B:PG4603 2.6 62.4 1.0 O2 B:PG4603 2.9 63.5 1.0 O3 B:PG4603 2.9 58.8 1.0 O4 B:PG4603 2.9 55.8 1.0 C8 B:PG4603 3.5 55.9 1.0 C B:GLN461 3.6 41.6 1.0 C1 B:PG4603 3.6 63.6 1.0 C7 B:PG4603 3.7 55.6 1.0 C6 B:PG4603 3.7 56.9 1.0 C2 B:PG4603 3.7 64.0 1.0 C3 B:PG4603 3.7 62.0 1.0 C5 B:PG4603 3.8 58.0 1.0 C4 B:PG4603 3.8 60.6 1.0 N B:GLU462 4.5 42.7 1.0 CA B:GLN461 4.5 41.1 1.0 CA B:GLU462 4.6 43.8 1.0 N B:GLN461 4.6 38.7 1.0 CG B:GLU462 4.7 46.5 1.0 CB B:GLN461 4.8 41.6 1.0

P.D.Kiser, P.D.Kiser. N/A N/A.