Sodium in PDB 7ice: Dna Polymerase Beta (E.C.2.7.7.7)/Dna Complex, Soaked in the Presence of CACL2

All present enzymatic activity of Dna Polymerase Beta (E.C.2.7.7.7)/Dna Complex, Soaked in the Presence of CACL2:
2.7.7.7;

The structure of Dna Polymerase Beta (E.C.2.7.7.7)/Dna Complex, Soaked in the Presence of CACL2, PDB code: 7ice was solved by H.Pelletier, M.R.Sawaya, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.80
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	178.469, 57.798, 48.444, 90.00, 90.00, 90.00
R / Rfree (%)	16.2 / n/a

The binding sites of Sodium atom in the Dna Polymerase Beta (E.C.2.7.7.7)/Dna Complex, Soaked in the Presence of CACL2 (pdb code 7ice). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Dna Polymerase Beta (E.C.2.7.7.7)/Dna Complex, Soaked in the Presence of CACL2, PDB code: 7ice:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Dna Polymerase Beta (E.C.2.7.7.7)/Dna Complex, Soaked in the Presence of CACL2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Dna Polymerase Beta (E.C.2.7.7.7)/Dna Complex, Soaked in the Presence of CACL2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na341 b:26.6 occ:1.00 O A:VAL103 2.1 18.5 1.0 O A:THR101 2.3 27.7 1.0 O A:ILE106 2.4 5.7 1.0 OP1 P:DG6 2.7 21.7 1.0 O A:HOH601 2.8 88.0 1.0 C A:VAL103 3.1 19.8 1.0 C A:THR101 3.3 20.4 1.0 C A:ILE106 3.5 7.5 1.0 N A:ILE106 3.6 14.8 1.0 P P:DG6 3.6 25.9 1.0 OP2 P:DG6 3.6 29.6 1.0 N A:VAL103 3.7 17.9 1.0 N A:GLY105 3.8 15.3 1.0 N A:SER104 3.9 20.6 1.0 CA A:SER104 3.9 22.3 1.0 C A:ARG102 4.0 25.0 1.0 CA A:VAL103 4.0 21.8 1.0 CA A:THR101 4.0 15.5 1.0 CA A:ILE106 4.1 11.6 1.0 N A:ARG102 4.3 16.9 1.0 C A:SER104 4.3 20.1 1.0 CA A:ARG102 4.4 21.5 1.0 CB A:ILE106 4.4 10.7 1.0 O A:ARG102 4.5 30.8 1.0 N A:GLY107 4.5 8.0 1.0 C A:GLY105 4.6 18.5 1.0 O3' P:DT5 4.7 31.4 1.0 O A:LEU100 4.7 30.8 1.0 CA A:GLY105 4.8 17.3 1.0 O5' P:DG6 4.8 27.1 1.0 CA A:GLY107 4.8 5.5 1.0 CG2 A:THR101 4.9 21.1 1.0 CB A:THR101 5.0 20.5 1.0

Sodium binding site 2 out of 2 in the Dna Polymerase Beta (E.C.2.7.7.7)/Dna Complex, Soaked in the Presence of CACL2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Dna Polymerase Beta (E.C.2.7.7.7)/Dna Complex, Soaked in the Presence of CACL2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na342 b:48.5 occ:1.00 OP1 P:DG3 3.4 31.5 1.0 OP2 P:DG3 4.0 46.8 1.0 P P:DG3 4.2 43.1 1.0 O P:HOH615 4.3 81.1 1.0

H.Pelletier, M.R.Sawaya, W.Wolfle, S.H.Wilson, J.Kraut. A Structural Basis For Metal Ion Mutagenicity and Nucleotide Selectivity in Human Dna Polymerase Beta Biochemistry V. 35 12762 1996.
ISSN: ISSN 0006-2960
PubMed: 8841119
DOI: 10.1021/BI9529566